DOSAGE REGIMENS FOR THE ADMINISTRATION OF A BISPECIFIC ANTIBODY IN COMBINATION WITH CHEMOTHERAPY

The present invention relates to dosage regimens for the administration of an antibody molecule which binds programmed death-ligand 1 (PD-L1) and lymphocyte-activation gene 3 (LAG-3) in combination with paclitaxel, and their medical use in the treatment of squamous cell carcinoma of the head and nec...

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Hauptverfasser: MULLINS, Stefanie, PATKI, Abhay, READER, Claire, MORROW, Michelle
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creator MULLINS, Stefanie
PATKI, Abhay
READER, Claire
MORROW, Michelle
description The present invention relates to dosage regimens for the administration of an antibody molecule which binds programmed death-ligand 1 (PD-L1) and lymphocyte-activation gene 3 (LAG-3) in combination with paclitaxel, and their medical use in the treatment of squamous cell carcinoma of the head and neck in human patients. La présente invention concerne des régimes posologiques pour l'administration d'une molécule d'anticorps qui se lie au ligand de mort programmée 1 (PD-L1) et au gène 3 d'activation des lymphocytes (LAG-3) en combinaison avec le paclitaxel, et leur utilisation médicale dans le traitement du carcinome à cellules squameuses de la tête et du cou chez des patients humains.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title DOSAGE REGIMENS FOR THE ADMINISTRATION OF A BISPECIFIC ANTIBODY IN COMBINATION WITH CHEMOTHERAPY
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