SERPINA-MODULATING COMPOSITIONS AND METHODS

The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Improved gRNA scaffolds compatible with St1Cas9 are described. L'invention con...

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Hauptverfasser: DONG, Xiaolong, COTTA-RAMUSINO, Cecilia Giovanna Silvia, JANCSO, Zsanett, MENDOZA, Alan Fabian, APPONI, Luciano Henrique, MIR, Aamir, BOTHMER, Anne Helen
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creator DONG, Xiaolong
COTTA-RAMUSINO, Cecilia Giovanna Silvia
JANCSO, Zsanett
MENDOZA, Alan Fabian
APPONI, Luciano Henrique
MIR, Aamir
BOTHMER, Anne Helen
description The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Improved gRNA scaffolds compatible with St1Cas9 are described. L'invention concerne, par exemple, des compositions, des systèmes et des procédés de ciblage, d'édition, de modification ou de manipulation d'un génome de cellule hôte à un ou plusieurs emplacements dans une séquence d'ADN dans une cellule, un tissu ou un sujet. L'invention concerne également des échafaudages d'ARNg améliorés compatibles avec St1Cas9.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title SERPINA-MODULATING COMPOSITIONS AND METHODS
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