MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE
The present disclosure relates to pharmaceutical compounds of the Formula I, Ia, Ib, or Ic or a pharmaceutically acceptable salt or composition thereof. Also provided are methods of use of TRPML modulators for treating disorders, the modulators including compounds of the Formula I, Ia, Ib, or Ic. Su...
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| creator | IYENGAR, Rajesh R LEE, Thomas Wai-Ho SCHMIDT, Darby R |
| description | The present disclosure relates to pharmaceutical compounds of the Formula I, Ia, Ib, or Ic or a pharmaceutically acceptable salt or composition thereof. Also provided are methods of use of TRPML modulators for treating disorders, the modulators including compounds of the Formula I, Ia, Ib, or Ic. Such methods of use include treatment of ciliopathies.
La présente invention concerne des composés pharmaceutiques de formule I, Ia, Ib, ou Ic ou un sel pharmaceutiquement acceptable ou une composition de ceux-ci. L'invention concerne également des procédés d'utilisation de modulateurs de TRPML pour traiter des troubles, les modulateurs comprenant des composés de formule I, Ia, Ib, ou Ic. De tels procédés d'utilisation comprennent le traitement de ciliopathies. |
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La présente invention concerne des composés pharmaceutiques de formule I, Ia, Ib, ou Ic ou un sel pharmaceutiquement acceptable ou une composition de ceux-ci. L'invention concerne également des procédés d'utilisation de modulateurs de TRPML pour traiter des troubles, les modulateurs comprenant des composés de formule I, Ia, Ib, ou Ic. De tels procédés d'utilisation comprennent le traitement de ciliopathies.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLDy9XcJ9XEM8Q8KVvB3UwgJCvD10VEI8XD1DFJw9vcN8A_2DPH09wtWcPRzUfB1DfHwdwErDA125WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGJoZmFoYGJo7GxsSpAgBgyCnz</recordid><startdate>20241017</startdate><enddate>20241017</enddate><creator>IYENGAR, Rajesh R</creator><creator>LEE, Thomas Wai-Ho</creator><creator>SCHMIDT, Darby R</creator><scope>EVB</scope></search><sort><creationdate>20241017</creationdate><title>MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE</title><author>IYENGAR, Rajesh R ; LEE, Thomas Wai-Ho ; SCHMIDT, Darby R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024168104A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>IYENGAR, Rajesh R</creatorcontrib><creatorcontrib>LEE, Thomas Wai-Ho</creatorcontrib><creatorcontrib>SCHMIDT, Darby R</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IYENGAR, Rajesh R</au><au>LEE, Thomas Wai-Ho</au><au>SCHMIDT, Darby R</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE</title><date>2024-10-17</date><risdate>2024</risdate><abstract>The present disclosure relates to pharmaceutical compounds of the Formula I, Ia, Ib, or Ic or a pharmaceutically acceptable salt or composition thereof. Also provided are methods of use of TRPML modulators for treating disorders, the modulators including compounds of the Formula I, Ia, Ib, or Ic. Such methods of use include treatment of ciliopathies.
La présente invention concerne des composés pharmaceutiques de formule I, Ia, Ib, ou Ic ou un sel pharmaceutiquement acceptable ou une composition de ceux-ci. L'invention concerne également des procédés d'utilisation de modulateurs de TRPML pour traiter des troubles, les modulateurs comprenant des composés de formule I, Ia, Ib, ou Ic. De tels procédés d'utilisation comprennent le traitement de ciliopathies.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE |
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