HISTIDINE KINASE INHIBITORS AS ANTIBACTERIAL AGENTS

The invention provides maleimide derivative compounds of Formula I, as histidine kinase inhibitors, useful for inhibiting bacterial histidine kinases, such as HK853 and AirS, for treating S. aureus bacterial infections, in particular methicillin-resistant S. aureus (MRSA). The invention further prov...

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Bibliographische Detailangaben

Hauptverfasser:	CARLSON, Erin Elizabeth, GOSWAMI, Manibarsha, JI, Yinduo, ESPINASSE, Adeline
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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