COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS
The disclosure describes compounds, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-CCP (anti-cyclic citrullinated peptide binding moiety). The compounds are useful in preventing, treating, and/or ameliorating various types of arthritis, includ...
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| creator | SPIEGEL, David MCDONALD, David DERAMON, Edward |
| description | The disclosure describes compounds, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-CCP (anti-cyclic citrullinated peptide binding moiety). The compounds are useful in preventing, treating, and/or ameliorating various types of arthritis, including rheumatoid arthritis (RA), in a subject when administered in therapeutically effective amounts.
La divulgation concerne des composés, qui, dans des aspects non limitatifs, contiennent une fraction de liaison de récepteur d'asialoglycoprotéine (ASGPR) et une fraction de liaison de peptide citrulliné anti-cyclique (anti-CCP). Les composés sont utiles dans la prévention, le traitement et/ou le soulagement de divers types d'arthrite, notamment la polyarthrite rhumatoïde (RA), chez un sujet lorsqu'ils sont administrés dans des quantités thérapeutiquement efficaces. |
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La divulgation concerne des composés, qui, dans des aspects non limitatifs, contiennent une fraction de liaison de récepteur d'asialoglycoprotéine (ASGPR) et une fraction de liaison de peptide citrulliné anti-cyclique (anti-CCP). Les composés sont utiles dans la prévention, le traitement et/ou le soulagement de divers types d'arthrite, notamment la polyarthrite rhumatoïde (RA), chez un sujet lorsqu'ils sont administrés dans des quantités thérapeutiquement efficaces.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241107&DB=EPODOC&CC=WO&NR=2024163610A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76419</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241107&DB=EPODOC&CC=WO&NR=2024163610A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SPIEGEL, David</creatorcontrib><creatorcontrib>MCDONALD, David</creatorcontrib><creatorcontrib>DERAMON, Edward</creatorcontrib><title>COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS</title><description>The disclosure describes compounds, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-CCP (anti-cyclic citrullinated peptide binding moiety). The compounds are useful in preventing, treating, and/or ameliorating various types of arthritis, including rheumatoid arthritis (RA), in a subject when administered in therapeutically effective amounts.
La divulgation concerne des composés, qui, dans des aspects non limitatifs, contiennent une fraction de liaison de récepteur d'asialoglycoprotéine (ASGPR) et une fraction de liaison de peptide citrulliné anti-cyclique (anti-CCP). Les composés sont utiles dans la prévention, le traitement et/ou le soulagement de divers types d'arthrite, notamment la polyarthrite rhumatoïde (RA), chez un sujet lorsqu'ils sont administrés dans des quantités thérapeutiquement efficaces.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPB09vcN8A_1cwlWcPRzUfB1DfHwB7Ld_IMUQoJcHUM8_dx1FBx9XX08_YOgPKBUQJBrmKsfiKvgGBTiEeQZ4hnMw8CalphTnMoLpbkZlN1cQ5w9dFML8uNTiwsSk1PzUkviw_2NDIxMDM2MzQwNHI2NiVMFAPYVLis</recordid><startdate>20241107</startdate><enddate>20241107</enddate><creator>SPIEGEL, David</creator><creator>MCDONALD, David</creator><creator>DERAMON, Edward</creator><scope>EVB</scope></search><sort><creationdate>20241107</creationdate><title>COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS</title><author>SPIEGEL, David ; MCDONALD, David ; DERAMON, Edward</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024163610A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>SPIEGEL, David</creatorcontrib><creatorcontrib>MCDONALD, David</creatorcontrib><creatorcontrib>DERAMON, Edward</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SPIEGEL, David</au><au>MCDONALD, David</au><au>DERAMON, Edward</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS</title><date>2024-11-07</date><risdate>2024</risdate><abstract>The disclosure describes compounds, which in non-limiting aspects contain an asialoglycoprotein receptor (ASGPR) binding moiety and an anti-CCP (anti-cyclic citrullinated peptide binding moiety). The compounds are useful in preventing, treating, and/or ameliorating various types of arthritis, including rheumatoid arthritis (RA), in a subject when administered in therapeutically effective amounts.
La divulgation concerne des composés, qui, dans des aspects non limitatifs, contiennent une fraction de liaison de récepteur d'asialoglycoprotéine (ASGPR) et une fraction de liaison de peptide citrulliné anti-cyclique (anti-CCP). Les composés sont utiles dans la prévention, le traitement et/ou le soulagement de divers types d'arthrite, notamment la polyarthrite rhumatoïde (RA), chez un sujet lorsqu'ils sont administrés dans des quantités thérapeutiquement efficaces.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | COMPOUNDS AND METHODS FOR TREATING, AMELIORATING, OR PREVENTING ARTHRITIS |
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