MICRONEEDLE PARTICLES, COMPOSITIONS, AND METHODS OF PARTICLE DEACTIVATION
STAR particles and compositions thereof, the STAR particles each having a core structure and one or more microneedle-like projections extending from the core structure. STAR particle compositions include a plurality of STAR particles configured for mechanical disruption of a biological tissue, and a...
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| creator | PRAUSNITZ, Mark R TADROS, Andrew |
| description | STAR particles and compositions thereof, the STAR particles each having a core structure and one or more microneedle-like projections extending from the core structure. STAR particle compositions include a plurality of STAR particles configured for mechanical disruption of a biological tissue, and a vehicle in which the plurality of STAR particles are dispersed, wherein the composition is adapted to contact the biological tissue surface in a manner to cause the STAR particles to mechanically disrupt the biological tissue, and subsequently to diminish the STAR particles' ability to mechanically disrupt a biological tissue by one or more deactivating mechanisms.
Particules STAR et des compositions de celles-ci, les particules STAR possédant chacune une structure de cœur et une ou plusieurs projections de type micro-aiguille s'étendant à partir de la structure de cœur. Les compositions de particules STAR comprennent une pluralité de particules STAR conçues pour la rupture mécanique d'un tissu biologique, et un véhicule dans lequel la pluralité de particules STAR est dispersée, la composition étant conçue pour entrer en contact avec la surface de tissu biologique de manière à amener les particules STAR à rompre mécaniquement le tissu biologique, puis à diminuer la capacité des particules STAR à perturber mécaniquement un tissu biologique par un ou plusieurs mécanismes de désactivation. |
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Particules STAR et des compositions de celles-ci, les particules STAR possédant chacune une structure de cœur et une ou plusieurs projections de type micro-aiguille s'étendant à partir de la structure de cœur. Les compositions de particules STAR comprennent une pluralité de particules STAR conçues pour la rupture mécanique d'un tissu biologique, et un véhicule dans lequel la pluralité de particules STAR est dispersée, la composition étant conçue pour entrer en contact avec la surface de tissu biologique de manière à amener les particules STAR à rompre mécaniquement le tissu biologique, puis à diminuer la capacité des particules STAR à perturber mécaniquement un tissu biologique par un ou plusieurs mécanismes de désactivation.</abstract><oa>free_for_read</oa></addata></record> |
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| language | eng ; fre |
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| subjects | DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | MICRONEEDLE PARTICLES, COMPOSITIONS, AND METHODS OF PARTICLE DEACTIVATION |
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