NOVEL IMIDAZOQUINOLINES WITH IMMUNOSTIMULATORY EFFECTS

Substituted imidazoquinoline ligands to TLR7 and 8 that up-regulate interferon production with improved specificity vs. existing ligands. The compounds exhibit improved pharmacokinetics and distribution properties and are well tolerated in vivo. They are suitable for use in therapeutics for infectio...

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Bibliographische Detailangaben

Hauptverfasser:	KEPPLER, Manuel, BAEUERLEIN, Christiane, BURNET, Michael, REISSER, Martin, GEIGER, Sophia, STRASS, Simon, EGGERS, Mary, GUSE, Jan-Hinrich
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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