RECOMBINANT POLIOVIRUS-LIKE PARTICLE VACCINE, PREPARATION METHOD THEREFOR AND USE THEREOF

Provided in the present invention are a recombinant poliovirus-like particle vaccine preparation, a preparation method therefor and the use thereof. The vaccine comprises recombinant virus-like particle antigens of three serotypes, and comprises an adjuvant. Preferably, the adjuvant is an aluminum a...

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Hauptverfasser: YANG, Yuyu, WEI, Bochao, LI, Hongyan, WEI, Mengyan, LI, Min, HAN, Qiqi, ZHU, Tao, YAN, Qiaoling, CHEN, Ying, SUI, Xiuwen
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creator YANG, Yuyu
WEI, Bochao
LI, Hongyan
WEI, Mengyan
LI, Min
HAN, Qiqi
ZHU, Tao
YAN, Qiaoling
CHEN, Ying
SUI, Xiuwen
description Provided in the present invention are a recombinant poliovirus-like particle vaccine preparation, a preparation method therefor and the use thereof. The vaccine comprises recombinant virus-like particle antigens of three serotypes, and comprises an adjuvant. Preferably, the adjuvant is an aluminum adjuvant. Preferably, the adjuvant is aluminum phosphate (AP), aluminum hydroxide treated with different concentrations of phosphates (PTAH), and aluminum hydroxide. La présente invention concerne une préparation de vaccin à particules de type poliovirus recombinant, son procédé de préparation et son utilisation. Le vaccin comprend des antigènes de particules de type virus recombinant de trois sérotypes, et comprend un adjuvant. De préférence, l'adjuvant est un adjuvant d'aluminium. De préférence, l'adjuvant est du phosphate d'aluminium (AP), de l'hydroxyde d'aluminium traité avec différentes concentrations de phosphates (PTAH), et de l'hydroxyde d'aluminium. 本发明提供了一种重组脊髓灰质炎病毒样颗粒疫苗制剂及其制备方法和应用,该疫苗包含三种血清型的重组病毒样颗粒抗原,且包
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title RECOMBINANT POLIOVIRUS-LIKE PARTICLE VACCINE, PREPARATION METHOD THEREFOR AND USE THEREOF
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