DIHYDRO-QUINAZOLINE, -BENZOTHIAZINE AND -BENZOXAZINE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTORS AGONISTS FOR TREATING OR PREVENTING NEUROLOGICAL DISEASES
The present invention is directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives for use in the prevention or treatment of neurological, psychiatric, sleep disorders and diseases, advantageously in which central orexin neurotransmission is compromised or in which central and per...
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| creator | KONOFAL, Eric LORMIER, Anh Tuan |
| description | The present invention is directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives for use in the prevention or treatment of neurological, psychiatric, sleep disorders and diseases, advantageously in which central orexin neurotransmission is compromised or in which central and peripheral orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds for use in the prevention and/or treatment of neurological disorders and diseases. The present invention is also directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives and the use of these compounds as a medicament.
La présente invention concerne des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine destinés à être utilisés dans la prévention ou le traitement de troubles et maladies neurologiques, psychiatriques et du sommeil, avantageusement dans lesquels une neurotransmission de l'orexine centrale est compromise ou dans lesquels des récepteurs de l'orexine centraux et périphériques sont impliqués. La présente invention concerne également des compositions pharmaceutiques comprenant ces composés destinés à être utilisés dans la prévention et/ou le traitement de troubles et de maladies neurologiques. La présente invention concerne également des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine et l'utilisation de ces composés comme médicament. |
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La présente invention concerne des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine destinés à être utilisés dans la prévention ou le traitement de troubles et maladies neurologiques, psychiatriques et du sommeil, avantageusement dans lesquels une neurotransmission de l'orexine centrale est compromise ou dans lesquels des récepteurs de l'orexine centraux et périphériques sont impliqués. La présente invention concerne également des compositions pharmaceutiques comprenant ces composés destinés à être utilisés dans la prévention et/ou le traitement de troubles et de maladies neurologiques. La présente invention concerne également des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine et l'utilisation de ces composés comme médicament.</description><language>eng ; fre</language><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240606&DB=EPODOC&CC=WO&NR=2024115797A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240606&DB=EPODOC&CC=WO&NR=2024115797A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KONOFAL, Eric</creatorcontrib><creatorcontrib>LORMIER, Anh Tuan</creatorcontrib><title>DIHYDRO-QUINAZOLINE, -BENZOTHIAZINE AND -BENZOXAZINE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTORS AGONISTS FOR TREATING OR PREVENTING NEUROLOGICAL DISEASES</title><description>The present invention is directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives for use in the prevention or treatment of neurological, psychiatric, sleep disorders and diseases, advantageously in which central orexin neurotransmission is compromised or in which central and peripheral orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds for use in the prevention and/or treatment of neurological disorders and diseases. The present invention is also directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives and the use of these compounds as a medicament.
La présente invention concerne des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine destinés à être utilisés dans la prévention ou le traitement de troubles et maladies neurologiques, psychiatriques et du sommeil, avantageusement dans lesquels une neurotransmission de l'orexine centrale est compromise ou dans lesquels des récepteurs de l'orexine centraux et périphériques sont impliqués. La présente invention concerne également des compositions pharmaceutiques comprenant ces composés destinés à être utilisés dans la prévention et/ou le traitement de troubles et de maladies neurologiques. La présente invention concerne également des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine et l'utilisation de ces composés comme médicament.</description><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNi8FqwlAQRbPpotj-w0C3BmpskS6feTfJQJix816iZiMir6vSCvZ7_FaD9QNcXc695z5mZ8_N1pvmnx2LG7RlwZTyJWTQ2LAbRiYn_lZt_gsP495F7hGuYxdAsYFBK3KB1LBhIUOJVVQbnVqFQwxUqVE0jFepR41Whh5yJUFn2mrNpWvJc4ALCE_Zw9f--5SebznJXirEssnT8XeXTsf9If2kv91ai9fibTZ7X3wsXDG_z7oAcwpGCg</recordid><startdate>20240606</startdate><enddate>20240606</enddate><creator>KONOFAL, Eric</creator><creator>LORMIER, Anh Tuan</creator><scope>EVB</scope></search><sort><creationdate>20240606</creationdate><title>DIHYDRO-QUINAZOLINE, -BENZOTHIAZINE AND -BENZOXAZINE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTORS AGONISTS FOR TREATING OR PREVENTING NEUROLOGICAL DISEASES</title><author>KONOFAL, Eric ; LORMIER, Anh Tuan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024115797A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><toplevel>online_resources</toplevel><creatorcontrib>KONOFAL, Eric</creatorcontrib><creatorcontrib>LORMIER, Anh Tuan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KONOFAL, Eric</au><au>LORMIER, Anh Tuan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DIHYDRO-QUINAZOLINE, -BENZOTHIAZINE AND -BENZOXAZINE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTORS AGONISTS FOR TREATING OR PREVENTING NEUROLOGICAL DISEASES</title><date>2024-06-06</date><risdate>2024</risdate><abstract>The present invention is directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives for use in the prevention or treatment of neurological, psychiatric, sleep disorders and diseases, advantageously in which central orexin neurotransmission is compromised or in which central and peripheral orexin receptors are involved. The present invention is also directed to pharmaceutical compositions comprising these compounds for use in the prevention and/or treatment of neurological disorders and diseases. The present invention is also directed to dihydro-quinazoline, -benzothiazine and -benzoxazine derivatives and the use of these compounds as a medicament.
La présente invention concerne des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine destinés à être utilisés dans la prévention ou le traitement de troubles et maladies neurologiques, psychiatriques et du sommeil, avantageusement dans lesquels une neurotransmission de l'orexine centrale est compromise ou dans lesquels des récepteurs de l'orexine centraux et périphériques sont impliqués. La présente invention concerne également des compositions pharmaceutiques comprenant ces composés destinés à être utilisés dans la prévention et/ou le traitement de troubles et de maladies neurologiques. La présente invention concerne également des dérivés de dihydro-quinazoline, -benzothiazine et -benzoxazine et l'utilisation de ces composés comme médicament.</abstract><oa>free_for_read</oa></addata></record> |
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| title | DIHYDRO-QUINAZOLINE, -BENZOTHIAZINE AND -BENZOXAZINE DERIVATIVES AND USE THEREOF AS OREXIN RECEPTORS AGONISTS FOR TREATING OR PREVENTING NEUROLOGICAL DISEASES |
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