METHOD OF PREPARING VASOPRESSIN
Methods of producing vasopressin are disclosed. The methods are based on solid phase peptide synthesis, partial deprotection and resin cleavage, purification, oxidation to a cyclic crude peptide and subsequent purification steps before isolation with high purity. Also disclosed are high purity vasop...
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| creator | FOMSGAARD, Jens HANSEN, Stefan |
| description | Methods of producing vasopressin are disclosed. The methods are based on solid phase peptide synthesis, partial deprotection and resin cleavage, purification, oxidation to a cyclic crude peptide and subsequent purification steps before isolation with high purity. Also disclosed are high purity vasopressins as obtained by the methods.
L'invention concerne des procédés de production de vasopressine. Les procédés comprennent les étapes de synthèse de peptides en phase solide, déprotection partielle et clivage de résine, purification, oxydation en un peptide brut cyclique ainsi que des étapes de purification ultérieures avant l'isolement avec une pureté élevée. L'invention concerne également des vasopressines de haute pureté telles qu'obtenues par les procédés. |
| format | Patent |
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L'invention concerne des procédés de production de vasopressine. Les procédés comprennent les étapes de synthèse de peptides en phase solide, déprotection partielle et clivage de résine, purification, oxydation en un peptide brut cyclique ainsi que des étapes de purification ultérieures avant l'isolement avec une pureté élevée. L'invention concerne également des vasopressines de haute pureté telles qu'obtenues par les procédés.</description><language>eng ; fre</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240530&DB=EPODOC&CC=WO&NR=2024112250A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240530&DB=EPODOC&CC=WO&NR=2024112250A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FOMSGAARD, Jens</creatorcontrib><creatorcontrib>HANSEN, Stefan</creatorcontrib><title>METHOD OF PREPARING VASOPRESSIN</title><description>Methods of producing vasopressin are disclosed. The methods are based on solid phase peptide synthesis, partial deprotection and resin cleavage, purification, oxidation to a cyclic crude peptide and subsequent purification steps before isolation with high purity. Also disclosed are high purity vasopressins as obtained by the methods.
L'invention concerne des procédés de production de vasopressine. Les procédés comprennent les étapes de synthèse de peptides en phase solide, déprotection partielle et clivage de résine, purification, oxydation en un peptide brut cyclique ainsi que des étapes de purification ultérieures avant l'isolement avec une pureté élevée. L'invention concerne également des vasopressines de haute pureté telles qu'obtenues par les procédés.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJD3dQ3x8HdR8HdTCAhyDXAM8vRzVwhzDPYH8oKDPf14GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgZGJoaGRkamBo6ExcaoAZNkilw</recordid><startdate>20240530</startdate><enddate>20240530</enddate><creator>FOMSGAARD, Jens</creator><creator>HANSEN, Stefan</creator><scope>EVB</scope></search><sort><creationdate>20240530</creationdate><title>METHOD OF PREPARING VASOPRESSIN</title><author>FOMSGAARD, Jens ; HANSEN, Stefan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024112250A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>FOMSGAARD, Jens</creatorcontrib><creatorcontrib>HANSEN, Stefan</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FOMSGAARD, Jens</au><au>HANSEN, Stefan</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD OF PREPARING VASOPRESSIN</title><date>2024-05-30</date><risdate>2024</risdate><abstract>Methods of producing vasopressin are disclosed. The methods are based on solid phase peptide synthesis, partial deprotection and resin cleavage, purification, oxidation to a cyclic crude peptide and subsequent purification steps before isolation with high purity. Also disclosed are high purity vasopressins as obtained by the methods.
L'invention concerne des procédés de production de vasopressine. Les procédés comprennent les étapes de synthèse de peptides en phase solide, déprotection partielle et clivage de résine, purification, oxydation en un peptide brut cyclique ainsi que des étapes de purification ultérieures avant l'isolement avec une pureté élevée. L'invention concerne également des vasopressines de haute pureté telles qu'obtenues par les procédés.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | METHOD OF PREPARING VASOPRESSIN |
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