INHIBITORS OF ROCK2
The present disclosure relates to inhibitors of Rho-associated protein kinase (ROCK), pharmaceutical compositions comprising the same, and use thereof for the prevention or treatment of a disease mediated by the ROCK. Particularly, the inhibitors of ROCK are selective for the inhibition of ROCK2. La...
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| creator | KLVANA, Martin WAKSAL, Samuel D JEDRZEJCZAK, Anna DOMAGALA, Dominik SOLUCH, Magdalena ZANIN-ZHOROV, Alexandra KACHKOVSKYI, Georgiy |
| description | The present disclosure relates to inhibitors of Rho-associated protein kinase (ROCK), pharmaceutical compositions comprising the same, and use thereof for the prevention or treatment of a disease mediated by the ROCK. Particularly, the inhibitors of ROCK are selective for the inhibition of ROCK2.
La présente divulgation concerne des inhibiteurs de la protéine kinase associée à Rho (ROCK), des compositions pharmaceutiques les comprenant, et leur utilisation pour la prévention ou le traitement d'une maladie médiée par la ROCK. En particulier, les inhibiteurs de ROCK sont sélectifs pour l'inhibition de ROCK2. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBITORS OF ROCK2 |
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