METHOD OF INHIBITING NUCLEAR FACTOR KAPPA B (NF-ΚB) ACTIVATION AND COMPOUNDS THEREOF

The present disclosure concerns methods of inhibiting nuclear factor kappa B (NF-KB) activation and compounds thereof. The method involves reducing p65 nuclear translocation in a cell using a compound of Formula (I) or a salt, solvate, stereoisomer or prodrug thereof. The present disclosure also con...

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Hauptverfasser:	CHAI, Li Lin, TRAN, Thi Ngoc Quy, LIAO, Wupeng, WONG, Wai-Shiu
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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