INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF
The disclosure provides compounds, in part, compounds of Formula I, Formula II or Formula III and their use in treating medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making compounds of the disclosure are...
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| creator | HAIRUO, Peng MUNOZ, Benito |
| description | The disclosure provides compounds, in part, compounds of Formula I, Formula II or Formula III and their use in treating medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making compounds of the disclosure are provided. The compounds are contemplated to be modulators, e.g., inhibitors, of cyclic ADP ribose hydrolase (CD38).
L'invention concerne des composés, en partie, des composés de formule I, de formule II ou de formule III et leur utilisation dans le traitement de maladies ou de troubles médicaux, tels que des maladies neurodégénératives, par exemple, la maladie de Parkinson. L'invention concerne également des compositions pharmaceutiques et des procédés de fabrication des composés de l'invention. Les composés sont considérés comme étant des modulateurs, par exemple des inhibiteurs, de l'ADP ribose hydrolase cyclique (CD38). |
| format | Patent |
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L'invention concerne des composés, en partie, des composés de formule I, de formule II ou de formule III et leur utilisation dans le traitement de maladies ou de troubles médicaux, tels que des maladies neurodégénératives, par exemple, la maladie de Parkinson. L'invention concerne également des compositions pharmaceutiques et des procédés de fabrication des composés de l'invention. Les composés sont considérés comme étant des modulateurs, par exemple des inhibiteurs, de l'ADP ribose hydrolase cyclique (CD38).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240516&DB=EPODOC&CC=WO&NR=2024102927A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25547,76298</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240516&DB=EPODOC&CC=WO&NR=2024102927A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HAIRUO, Peng</creatorcontrib><creatorcontrib>MUNOZ, Benito</creatorcontrib><title>INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF</title><description>The disclosure provides compounds, in part, compounds of Formula I, Formula II or Formula III and their use in treating medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making compounds of the disclosure are provided. The compounds are contemplated to be modulators, e.g., inhibitors, of cyclic ADP ribose hydrolase (CD38).
L'invention concerne des composés, en partie, des composés de formule I, de formule II ou de formule III et leur utilisation dans le traitement de maladies ou de troubles médicaux, tels que des maladies neurodégénératives, par exemple, la maladie de Parkinson. L'invention concerne également des compositions pharmaceutiques et des procédés de fabrication des composés de l'invention. Les composés sont considérés comme étant des modulateurs, par exemple des inhibiteurs, de l'ADP ribose hydrolase cyclique (CD38).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHDw9PPwdPIM8Q8KVvB3U3COdPbxdFZwdAlQCPJ08g92VfCIdAny93EEsnxdQzz8XcDKQoHcEA_XIFd_Nx4G1rTEnOJUXijNzaDs5hri7KGbWpAfn1pckJicmpdaEh_ub2RgZGJoYGRpZO5oaEycKgA_9ytf</recordid><startdate>20240516</startdate><enddate>20240516</enddate><creator>HAIRUO, Peng</creator><creator>MUNOZ, Benito</creator><scope>EVB</scope></search><sort><creationdate>20240516</creationdate><title>INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF</title><author>HAIRUO, Peng ; MUNOZ, Benito</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024102927A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HAIRUO, Peng</creatorcontrib><creatorcontrib>MUNOZ, Benito</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HAIRUO, Peng</au><au>MUNOZ, Benito</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF</title><date>2024-05-16</date><risdate>2024</risdate><abstract>The disclosure provides compounds, in part, compounds of Formula I, Formula II or Formula III and their use in treating medical diseases or disorders, such as neurodegenerative diseases, e.g., Parkinson's disease. Pharmaceutical compositions and methods of making compounds of the disclosure are provided. The compounds are contemplated to be modulators, e.g., inhibitors, of cyclic ADP ribose hydrolase (CD38).
L'invention concerne des composés, en partie, des composés de formule I, de formule II ou de formule III et leur utilisation dans le traitement de maladies ou de troubles médicaux, tels que des maladies neurodégénératives, par exemple, la maladie de Parkinson. L'invention concerne également des compositions pharmaceutiques et des procédés de fabrication des composés de l'invention. Les composés sont considérés comme étant des modulateurs, par exemple des inhibiteurs, de l'ADP ribose hydrolase cyclique (CD38).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE METHODS OF USE THEREOF |
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