MULTISPECIFIC MOLECULES FOR CLEARANCE OF IMMUNOGLOBULINS IN THE TREATMENT OF AUTOANTIBODY-INDUCED DISEASES

The present invention is directed to multispecific molecules that bind immunoglobulin and a recycling target. Binding immunoglobulin and a recycling target results in degradation of immunoglobulin and in certain embodiments recycling of the multispecific molecule. The multispecific molecules of the...

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Hauptverfasser: DEVANABOYINA, Venkata Siva Charan, LI, Peng
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creator DEVANABOYINA, Venkata Siva Charan
LI, Peng
description The present invention is directed to multispecific molecules that bind immunoglobulin and a recycling target. Binding immunoglobulin and a recycling target results in degradation of immunoglobulin and in certain embodiments recycling of the multispecific molecule. The multispecific molecules of the present invention are thought to be useful in the treatment of autoantibody-induced diseases. La présente invention concerne des molécules multispécifiques qui se lient à l'immunoglobuline et une cible de recyclage La liaison de l'immunoglobuline et d'une cible de recyclage entraîne la dégradation de l'immunoglobuline et, dans certains modes de réalisation, le recyclage de la molécule multispécifique. Les molécules multispécifiques de la présente invention sont considérées comme étant utiles dans le traitement de maladies induites par des auto-anticorps.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MULTISPECIFIC MOLECULES FOR CLEARANCE OF IMMUNOGLOBULINS IN THE TREATMENT OF AUTOANTIBODY-INDUCED DISEASES
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