ESTER ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE

The disclosure relates to compounds, compositions, methods and uses relating to activation of one or more serotonin receptors (i.e., 5-HT2 receptors). Specifically, the disclosure provides ester derivatives of psilocin and related tryptamines, and methods for treating neurological diseases or disord...

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Hauptverfasser: KAUR, Harpreet, ALI, Ahmed Magdy, DOVE, Peter, O'MEARA, Jeffrey
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creator KAUR, Harpreet
ALI, Ahmed Magdy
DOVE, Peter
O'MEARA, Jeffrey
description The disclosure relates to compounds, compositions, methods and uses relating to activation of one or more serotonin receptors (i.e., 5-HT2 receptors). Specifically, the disclosure provides ester derivatives of psilocin and related tryptamines, and methods for treating neurological diseases or disorders, including neurodegenerative diseases, pain, and/or psychiatric disorders that comprise the compounds or compositions thereof. Also provided are methods for preparing the compounds described herein. La divulgation concerne des composés, des compositions, des procédés et des utilisations se rapportant à l'activation d'un ou de plusieurs récepteurs de sérotonine (c'est-à-dire des récepteurs 5-HT2). Spécifiquement, la divulgation concerne des dérivés esters de psilocine et des tryptamines associées, et des méthodes de traitement de maladies ou de troubles neurologiques, comprenant des maladies neurodégénératives, la douleur et/ou des troubles psychiatriques qui comprennent les composés ou les compositions de ceux-ci. L'invention concerne également des procédés de préparation des composés décrits ici.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title ESTER ANALOGS OF PSILOCIN, PROCESSES FOR THE PREPARATION THEREOF, AND METHODS OF USE
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