PSEUDO-VIRAL SYSTEMS FOR MUTATIONAL SCANNING OF VIRAL PROTEINS

Cell-stored barcoded viral protein libraries with are described. The libraries can be used to map resistance mutations to therapeutic treatments. The libraries include features that allow efficient collection and assessment of informative data, obviating many bottlenecks of previous approaches. Sont...

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Hauptverfasser:	BLOOM, Jesse, RADFORD, Caelan, CRAWFORD, Katharine Dusenbury, DADONAITE, Bernadeta
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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creator	BLOOM, Jesse RADFORD, Caelan CRAWFORD, Katharine Dusenbury DADONAITE, Bernadeta
description	Cell-stored barcoded viral protein libraries with are described. The libraries can be used to map resistance mutations to therapeutic treatments. The libraries include features that allow efficient collection and assessment of informative data, obviating many bottlenecks of previous approaches. Sont décrites des bibliothèques de protéines virales à code-barres stockées dans des cellules. Les bibliothèques peuvent être utilisées pour apparier des mutations de résistance avec des traitements thérapeutiques. Les bibliothèques comprennent des caractéristiques qui permettent une collecte et une évaluation efficaces de données informatives, ce qui permet d'éviter les nombreux goulots d'étranglement des approches précédentes.
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subjects	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
title	PSEUDO-VIRAL SYSTEMS FOR MUTATIONAL SCANNING OF VIRAL PROTEINS
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