DMD ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIPPING EFFICIENCY
Provided herein are oligonucleotides, cell-penetrating peptides, and peptide- oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides,...
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| creator | WU, Chia-Ling GOOSSENS, Remko AARTSMA-RUS, Annemieke VERWEY, Nisha ARIYUREK, Yavuz SCHNELL, Frederick Joseph |
| description | Provided herein are oligonucleotides, cell-penetrating peptides, and peptide- oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.
L'invention concerne des oligonucléotides, des peptides de pénétration cellulaire et des conjugués peptide-oligonucléotide. L'invention concerne également des méthodes de traitement d'une maladie musculaire, d'une infection virale, ou d'une infection bactérienne chez un sujet ayant besoin d'un tel traitement, comprenant l'administration au sujet d'oligonucléotides, de peptides et de conjugués peptide-oligonucléotide décrits dans la description. |
| format | Patent |
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L'invention concerne des oligonucléotides, des peptides de pénétration cellulaire et des conjugués peptide-oligonucléotide. L'invention concerne également des méthodes de traitement d'une maladie musculaire, d'une infection virale, ou d'une infection bactérienne chez un sujet ayant besoin d'un tel traitement, comprenant l'administration au sujet d'oligonucléotides, de peptides et de conjugués peptide-oligonucléotide décrits dans la description.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240328&DB=EPODOC&CC=WO&NR=2024064237A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25555,76308</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240328&DB=EPODOC&CC=WO&NR=2024064237A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WU, Chia-Ling</creatorcontrib><creatorcontrib>GOOSSENS, Remko</creatorcontrib><creatorcontrib>AARTSMA-RUS, Annemieke</creatorcontrib><creatorcontrib>VERWEY, Nisha</creatorcontrib><creatorcontrib>ARIYUREK, Yavuz</creatorcontrib><creatorcontrib>SCHNELL, Frederick Joseph</creatorcontrib><title>DMD ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIPPING EFFICIENCY</title><description>Provided herein are oligonucleotides, cell-penetrating peptides, and peptide- oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.
L'invention concerne des oligonucléotides, des peptides de pénétration cellulaire et des conjugués peptide-oligonucléotide. L'invention concerne également des méthodes de traitement d'une maladie musculaire, d'une infection virale, ou d'une infection bactérienne chez un sujet ayant besoin d'un tel traitement, comprenant l'administration au sujet d'oligonucléotides, de peptides et de conjugués peptide-oligonucléotide décrits dans la description.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLB38XVRcPQL8Qx29Qt2VfD38XT39wt19nH1D_F0cdX1dXXxdAxxdVFwjfD3Uwj29gwI8PRzV3B1c_N09nT1c47kYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBkYmBmYmRsbmjkbGxKkCAD_BK3c</recordid><startdate>20240328</startdate><enddate>20240328</enddate><creator>WU, Chia-Ling</creator><creator>GOOSSENS, Remko</creator><creator>AARTSMA-RUS, Annemieke</creator><creator>VERWEY, Nisha</creator><creator>ARIYUREK, Yavuz</creator><creator>SCHNELL, Frederick Joseph</creator><scope>EVB</scope></search><sort><creationdate>20240328</creationdate><title>DMD ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIPPING EFFICIENCY</title><author>WU, Chia-Ling ; GOOSSENS, Remko ; AARTSMA-RUS, Annemieke ; VERWEY, Nisha ; ARIYUREK, Yavuz ; SCHNELL, Frederick Joseph</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024064237A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>WU, Chia-Ling</creatorcontrib><creatorcontrib>GOOSSENS, Remko</creatorcontrib><creatorcontrib>AARTSMA-RUS, Annemieke</creatorcontrib><creatorcontrib>VERWEY, Nisha</creatorcontrib><creatorcontrib>ARIYUREK, Yavuz</creatorcontrib><creatorcontrib>SCHNELL, Frederick Joseph</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WU, Chia-Ling</au><au>GOOSSENS, Remko</au><au>AARTSMA-RUS, Annemieke</au><au>VERWEY, Nisha</au><au>ARIYUREK, Yavuz</au><au>SCHNELL, Frederick Joseph</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DMD ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIPPING EFFICIENCY</title><date>2024-03-28</date><risdate>2024</risdate><abstract>Provided herein are oligonucleotides, cell-penetrating peptides, and peptide- oligonucleotide-conjugates. Also provided herein are methods of treating a muscle disease, a viral infection, or a bacterial infection in a subject in need thereof, comprising administering to the subject oligonucleotides, peptides, and peptide-oligonucleotide-conjugates described herein.
L'invention concerne des oligonucléotides, des peptides de pénétration cellulaire et des conjugués peptide-oligonucléotide. L'invention concerne également des méthodes de traitement d'une maladie musculaire, d'une infection virale, ou d'une infection bactérienne chez un sujet ayant besoin d'un tel traitement, comprenant l'administration au sujet d'oligonucléotides, de peptides et de conjugués peptide-oligonucléotide décrits dans la description.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | DMD ANTISENSE OLIGONUCLEOTIDE-MEDIATED EXON SKIPPING EFFICIENCY |
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