CHARACTERISTIC IMPURITY IN EMPAGLIFLOZIN BULK DRUG OR PREPARATION AND USE THEREOF
Provided are a characteristic impurity in an empagliflozin bulk drug or preparation and use thereof, and further provided are a detection method, a synthesis method, in-vitro pharmacological activity and in-vitro toxicity of the impurity. The present invention provides an important basis for quality...
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| creator | ZHANG, Feng PAN, Yingwei MEI, Guangyao XU, Xiaoyang XU, Chenli WANG, Zikang XI, Junqing WANG, Haibo JIN, Hui WU, Yujuan BAI, Xugang XIAO, Yang CHEN, Antu YU, Lixia MENG, Haiping |
| description | Provided are a characteristic impurity in an empagliflozin bulk drug or preparation and use thereof, and further provided are a detection method, a synthesis method, in-vitro pharmacological activity and in-vitro toxicity of the impurity. The present invention provides an important basis for quality control of an empagliflozin bulk drug or preparation, and is of great significance to quality control of the empagliflozin bulk drug or preparation.
L'invention concerne une impureté caractéristique d'un médicament ou d'une préparation en vrac d'empagliflozine et son utilisation, et concerne en outre un procédé de détection, un procédé de synthèse, une activité pharmacologique in vitro et une toxicité in vitro de l'impureté. La présente invention offre une base importante pour le contrôle de qualité d'un médicament ou d'une préparation en vrac d'empagliflozine, et est d'une grande importance pour le contrôle de qualité du médicament ou de la préparation en vrac d'empagliflozine.
一种恩格列净原料药或制剂中的特征杂质和应用，并提供了该杂质的检测方法、 |
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L'invention concerne une impureté caractéristique d'un médicament ou d'une préparation en vrac d'empagliflozine et son utilisation, et concerne en outre un procédé de détection, un procédé de synthèse, une activité pharmacologique in vitro et une toxicité in vitro de l'impureté. La présente invention offre une base importante pour le contrôle de qualité d'un médicament ou d'une préparation en vrac d'empagliflozine, et est d'une grande importance pour le contrôle de qualité du médicament ou de la préparation en vrac d'empagliflozine.
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L'invention concerne une impureté caractéristique d'un médicament ou d'une préparation en vrac d'empagliflozine et son utilisation, et concerne en outre un procédé de détection, un procédé de synthèse, une activité pharmacologique in vitro et une toxicité in vitro de l'impureté. La présente invention offre une base importante pour le contrôle de qualité d'un médicament ou d'une préparation en vrac d'empagliflozine, et est d'une grande importance pour le contrôle de qualité du médicament ou de la préparation en vrac d'empagliflozine.
一种恩格列净原料药或制剂中的特征杂质和应用，并提供了该杂质的检测方法、</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAh09nAMcnQOcQ3yDA7xdFbw9A0IDfIMiVTw9FNw9Q1wdPfxdPPxjwLynEJ9vBVcgkLdFfyDFAKCXAOA-kI8_f0UHP1cFEKDXRVCPFyDXP3deBhY0xJzilN5oTQ3g7Kba4izh25qQX58anFBYnJqXmpJfLi_kYGRiYGZgZG5oaOhMXGqAH_oMF8</recordid><startdate>20240328</startdate><enddate>20240328</enddate><creator>ZHANG, Feng</creator><creator>PAN, Yingwei</creator><creator>MEI, Guangyao</creator><creator>XU, Xiaoyang</creator><creator>XU, Chenli</creator><creator>WANG, Zikang</creator><creator>XI, Junqing</creator><creator>WANG, Haibo</creator><creator>JIN, Hui</creator><creator>WU, Yujuan</creator><creator>BAI, Xugang</creator><creator>XIAO, Yang</creator><creator>CHEN, Antu</creator><creator>YU, Lixia</creator><creator>MENG, Haiping</creator><scope>EVB</scope></search><sort><creationdate>20240328</creationdate><title>CHARACTERISTIC IMPURITY IN EMPAGLIFLOZIN BULK DRUG OR PREPARATION AND USE THEREOF</title><author>ZHANG, Feng ; PAN, Yingwei ; MEI, Guangyao ; XU, Xiaoyang ; XU, Chenli ; WANG, Zikang ; XI, Junqing ; WANG, Haibo ; JIN, Hui ; WU, Yujuan ; BAI, Xugang ; XIAO, Yang ; CHEN, Antu ; YU, Lixia ; MENG, Haiping</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024060271A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZHANG, Feng</creatorcontrib><creatorcontrib>PAN, Yingwei</creatorcontrib><creatorcontrib>MEI, Guangyao</creatorcontrib><creatorcontrib>XU, Xiaoyang</creatorcontrib><creatorcontrib>XU, Chenli</creatorcontrib><creatorcontrib>WANG, Zikang</creatorcontrib><creatorcontrib>XI, Junqing</creatorcontrib><creatorcontrib>WANG, Haibo</creatorcontrib><creatorcontrib>JIN, Hui</creatorcontrib><creatorcontrib>WU, Yujuan</creatorcontrib><creatorcontrib>BAI, Xugang</creatorcontrib><creatorcontrib>XIAO, Yang</creatorcontrib><creatorcontrib>CHEN, Antu</creatorcontrib><creatorcontrib>YU, Lixia</creatorcontrib><creatorcontrib>MENG, Haiping</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZHANG, Feng</au><au>PAN, Yingwei</au><au>MEI, Guangyao</au><au>XU, Xiaoyang</au><au>XU, Chenli</au><au>WANG, Zikang</au><au>XI, Junqing</au><au>WANG, Haibo</au><au>JIN, Hui</au><au>WU, Yujuan</au><au>BAI, Xugang</au><au>XIAO, Yang</au><au>CHEN, Antu</au><au>YU, Lixia</au><au>MENG, Haiping</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>CHARACTERISTIC IMPURITY IN EMPAGLIFLOZIN BULK DRUG OR PREPARATION AND USE THEREOF</title><date>2024-03-28</date><risdate>2024</risdate><abstract>Provided are a characteristic impurity in an empagliflozin bulk drug or preparation and use thereof, and further provided are a detection method, a synthesis method, in-vitro pharmacological activity and in-vitro toxicity of the impurity. The present invention provides an important basis for quality control of an empagliflozin bulk drug or preparation, and is of great significance to quality control of the empagliflozin bulk drug or preparation.
L'invention concerne une impureté caractéristique d'un médicament ou d'une préparation en vrac d'empagliflozine et son utilisation, et concerne en outre un procédé de détection, un procédé de synthèse, une activité pharmacologique in vitro et une toxicité in vitro de l'impureté. La présente invention offre une base importante pour le contrôle de qualité d'un médicament ou d'une préparation en vrac d'empagliflozine, et est d'une grande importance pour le contrôle de qualité du médicament ou de la préparation en vrac d'empagliflozine.
一种恩格列净原料药或制剂中的特征杂质和应用，并提供了该杂质的检测方法、</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS |
| title | CHARACTERISTIC IMPURITY IN EMPAGLIFLOZIN BULK DRUG OR PREPARATION AND USE THEREOF |
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