SULFONE-SUBSTITUTED PYRIDO[3,4-D]PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF CANCER

The application relates to sulfone-substituted pyrido[3,4-d]pyrimidine compounds of general formula (I), to pharmaceutical compositions and combinations comprising them and their medical use for the treatment or prophylaxis of hyperproliferative disorders. L'invention concerne des composés de p...

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Hauptverfasser: WARZOK, Ulrike, STELLFELD, Timo, ARLT, Matthias, ERKELENZ, Michael, SIEMEISTER, Gerhard, SCHRÖDER, Jens, PAPE, Felix, GRAHAM, Keith, GRESSIES, Steffen, CHEUNG, Shing Hu, MENZ, Stephan, HETHEY, Christoph Philipp, SCHULZE, Volker, BAIRLEIN, Michaela, MORTIER, Jeremie Xavier G, HILLIG, Roman, LANG, Dieter
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The application relates to sulfone-substituted pyrido[3,4-d]pyrimidine compounds of general formula (I), to pharmaceutical compositions and combinations comprising them and their medical use for the treatment or prophylaxis of hyperproliferative disorders. L'invention concerne des composés de pyrido[3,4-d]pyrimidine substitués par sulfone de formule générale (I), des compositions pharmaceutiques et des combinaisons les comprenant et leur utilisation médicale pour le traitement ou la prophylaxie de troubles hyperprolifératifs.