PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED
Disclosed herein are small molecule modulators of pannexin. Also disclosed herein are methods of treating disorders associated with exacerbated activation of ATP- induced signal pathways mediated by pannexin, such as pain and opioid addiction, by administering small molecule modulators of pannexin....
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| creator | LÓPEZ, David Alexandre GROSS, Gerhard Max |
| description | Disclosed herein are small molecule modulators of pannexin. Also disclosed herein are methods of treating disorders associated with exacerbated activation of ATP- induced signal pathways mediated by pannexin, such as pain and opioid addiction, by administering small molecule modulators of pannexin.
L'invention concerne des modulateurs à petites molécules de la pannexine. L'invention concerne également des méthodes de traitement de troubles associés à l'activation exacerbée de voies de signal induites par l'ATP médiées par la pannexine, telles que la douleur et la dépendance aux opioïdes, par l'administration de modulateurs à petites molécules de la pannexine. |
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L'invention concerne des modulateurs à petites molécules de la pannexine. L'invention concerne également des méthodes de traitement de troubles associés à l'activation exacerbée de voies de signal induites par l'ATP médiées par la pannexine, telles que la douleur et la dépendance aux opioïdes, par l'administration de modulateurs à petites molécules de la pannexine.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZIgMcPTzc43w9NM1VPD1dwn1cQzxDwpWcPRzUfB1DfHwdwlW8HdTCAlydQzx9HNXcPEM9g9ycQWq8PRTCPfwdPZQQDLAEyjsG-Dj6ewY4urCw8CalphTnMoLpbkZlN1cQ5w9dFML8uNTiwsSk1PzUkviw_2NDIxMDEwsLY0sHY2MiVMFAMevMjc</recordid><startdate>20240307</startdate><enddate>20240307</enddate><creator>LÓPEZ, David Alexandre</creator><creator>GROSS, Gerhard Max</creator><scope>EVB</scope></search><sort><creationdate>20240307</creationdate><title>PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED</title><author>LÓPEZ, David Alexandre ; GROSS, Gerhard Max</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024049929A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>LÓPEZ, David Alexandre</creatorcontrib><creatorcontrib>GROSS, Gerhard Max</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LÓPEZ, David Alexandre</au><au>GROSS, Gerhard Max</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED</title><date>2024-03-07</date><risdate>2024</risdate><abstract>Disclosed herein are small molecule modulators of pannexin. Also disclosed herein are methods of treating disorders associated with exacerbated activation of ATP- induced signal pathways mediated by pannexin, such as pain and opioid addiction, by administering small molecule modulators of pannexin.
L'invention concerne des modulateurs à petites molécules de la pannexine. L'invention concerne également des méthodes de traitement de troubles associés à l'activation exacerbée de voies de signal induites par l'ATP médiées par la pannexine, telles que la douleur et la dépendance aux opioïdes, par l'administration de modulateurs à petites molécules de la pannexine.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | PANNEXIN-1 MODULATORS AND METHODS OF TREATING DISORDERS IN WHICH PANNEXIN-1 IS IMPLICATED |
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