METHODS FOR INCREASING THE BIOAVAILABILITY OF NUCLEOSIDE MEDICINAL AGENTS

Provided are methods for increasing the bioavailability of nucleoside medicinal agents in treating mitochondrial depletion syndromes. In particular, the methods relate to increasing the bioavailability of deoxycytidine and deoxythymidine by administering a therapeutically effective amount of deoxycy...

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description Provided are methods for increasing the bioavailability of nucleoside medicinal agents in treating mitochondrial depletion syndromes. In particular, the methods relate to increasing the bioavailability of deoxycytidine and deoxythymidine by administering a therapeutically effective amount of deoxycytidine and deoxythymidine with food. L'invention concerne des méthodes pour augmenter la biodisponibilité d'agents médicinaux nucléosidiques dans le traitement de syndromes de déplétion mitochondriale. En particulier, les méthodes concernent l'augmentation de la biodisponibilité de la désoxycytidine et de la désoxythymidine par l'administration d'une quantité thérapeutiquement efficace de désoxycytidine et de désoxythymidine avec des aliments.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHODS FOR INCREASING THE BIOAVAILABILITY OF NUCLEOSIDE MEDICINAL AGENTS
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