INHIBITORS OF CORONAVIRUS

The present invention relates to novel compounds of Formula (I) (cyanophenyl/cyanopyridinyl- 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine amide compounds) for treating and/or preventing infection or diseases caused by coronavirus. The invention is also directed to pharmaceutical compositions comp...

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Bibliographische Detailangaben
Hauptverfasser:	ALONSO DE DIEGO, Sergio Alvar, BUYCK, Christophe Francis Robert Nestor, JOUFFROY, Matthieu Dominique, VAN DAMME, Ellen, VAN LOOCK, Marnix, GHOSH, Brahmananda, TEMMERMAN, Koen Boudewijn A, VAN GOOL, Michiel Luc Maria, GÓMEZ PULIDO, José Enrique
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to novel compounds of Formula (I) (cyanophenyl/cyanopyridinyl- 4-oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine amide compounds) for treating and/or preventing infection or diseases caused by coronavirus. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and/or treatment of coronavirus infection. La présente invention concerne de nouveaux composés de formule (I) (cyanophényl/cyanopyridinyl-4-oxo-4,5,6,7-tétrahydropyrazolo[1,5- a]pyrazine amide) pour traiter et/ou prévenir une infection ou des maladies provoquées par un coronavirus. L'invention concerne également des compositions pharmaceutiques comprenant de tels composés, des procédés de préparation de tels composés et de telles compositions, et l'utilisation de tels composés et de telles compositions pour la prévention ou le traitement d'une infection à coronavirus.