METHOD FOR IDENTIFYING DEMENTIA WITH LEWY BODIES IN A SUBJECT

It is provided a method for identifying dementia with Lewy bodies (DLB) in a subject, comprising determining in a sample of the subject comprising mitochondrial DNA, the methylation pattern in the D- loop region and/or ND1 gene of the mitochondrial DNA. Further, a classification model, oligonucleoti...

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Bibliographische Detailangaben
Hauptverfasser:	BLANCH LOZANO, Marta, BARRACHINA CASTILLO, Marta, MOSQUERA MAYO, Jose Luis
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	It is provided a method for identifying dementia with Lewy bodies (DLB) in a subject, comprising determining in a sample of the subject comprising mitochondrial DNA, the methylation pattern in the D- loop region and/or ND1 gene of the mitochondrial DNA. Further, a classification model, oligonucleotides and kits to perform the method are also provided. L'invention concerne un procédé d'identification de la démence à corps de Lewy (DLB) chez un sujet, comprenant la détermination, dans un échantillon prélevé sur le sujet et comprenant de l'ADN mitochondrial, du schéma de méthylation dans la région de la boucle D et/ou dans le gène ND1 de l'ADN mitochondrial. L'invention concerne en outre un modèle de classification, des oligonucléotides et des kits pour mettre en oeuvre le procédé.