TREM2 MODULATORS
The present invention relates to compounds useful for modulating Triggering Receptor Expressed on Myeloid Cells 2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as neurodegenerative diseases and to pharma...
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| creator | MEISSNER, Johannes Wilhelm Georg BUSCH-PETERSEN, Jakob WHITLOCK, Gavin EMMERICH, Juliette |
| description | The present invention relates to compounds useful for modulating Triggering Receptor Expressed on Myeloid Cells 2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as neurodegenerative diseases and to pharmaceutical compositions comprising the compounds.
La présente invention concerne des composés utiles pour moduler un récepteur de déclenchement exprimé sur les cellules myéloïdes 2 ("TREM2"). L'invention concerne également les composés destinés à être utilisés dans le traitement d'affections liées à la perte de fonction de TREM2, telles que des maladies neurodégénératives, ainsi que des compositions pharmaceutiques comprenant les composés. |
| format | Patent |
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La présente invention concerne des composés utiles pour moduler un récepteur de déclenchement exprimé sur les cellules myéloïdes 2 ("TREM2"). L'invention concerne également les composés destinés à être utilisés dans le traitement d'affections liées à la perte de fonction de TREM2, telles que des maladies neurodégénératives, ainsi que des compositions pharmaceutiques comprenant les composés.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240222&DB=EPODOC&CC=WO&NR=2024008722A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240222&DB=EPODOC&CC=WO&NR=2024008722A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MEISSNER, Johannes Wilhelm Georg</creatorcontrib><creatorcontrib>BUSCH-PETERSEN, Jakob</creatorcontrib><creatorcontrib>WHITLOCK, Gavin</creatorcontrib><creatorcontrib>EMMERICH, Juliette</creatorcontrib><title>TREM2 MODULATORS</title><description>The present invention relates to compounds useful for modulating Triggering Receptor Expressed on Myeloid Cells 2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as neurodegenerative diseases and to pharmaceutical compositions comprising the compounds.
La présente invention concerne des composés utiles pour moduler un récepteur de déclenchement exprimé sur les cellules myéloïdes 2 ("TREM2"). L'invention concerne également les composés destinés à être utilisés dans le traitement d'affections liées à la perte de fonction de TREM2, telles que des maladies neurodégénératives, ainsi que des compositions pharmaceutiques comprenant les composés.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBAICXL1NVLw9XcJ9XEM8Q8K5mFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGJgYGFuZGRo7GxsSpAgB9IB51</recordid><startdate>20240222</startdate><enddate>20240222</enddate><creator>MEISSNER, Johannes Wilhelm Georg</creator><creator>BUSCH-PETERSEN, Jakob</creator><creator>WHITLOCK, Gavin</creator><creator>EMMERICH, Juliette</creator><scope>EVB</scope></search><sort><creationdate>20240222</creationdate><title>TREM2 MODULATORS</title><author>MEISSNER, Johannes Wilhelm Georg ; BUSCH-PETERSEN, Jakob ; WHITLOCK, Gavin ; EMMERICH, Juliette</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024008722A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MEISSNER, Johannes Wilhelm Georg</creatorcontrib><creatorcontrib>BUSCH-PETERSEN, Jakob</creatorcontrib><creatorcontrib>WHITLOCK, Gavin</creatorcontrib><creatorcontrib>EMMERICH, Juliette</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MEISSNER, Johannes Wilhelm Georg</au><au>BUSCH-PETERSEN, Jakob</au><au>WHITLOCK, Gavin</au><au>EMMERICH, Juliette</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>TREM2 MODULATORS</title><date>2024-02-22</date><risdate>2024</risdate><abstract>The present invention relates to compounds useful for modulating Triggering Receptor Expressed on Myeloid Cells 2 ("TREM2"). The invention also relates to the compounds for use in treatment of conditions related to loss of function of TREM2, such as neurodegenerative diseases and to pharmaceutical compositions comprising the compounds.
La présente invention concerne des composés utiles pour moduler un récepteur de déclenchement exprimé sur les cellules myéloïdes 2 ("TREM2"). L'invention concerne également les composés destinés à être utilisés dans le traitement d'affections liées à la perte de fonction de TREM2, telles que des maladies neurodégénératives, ainsi que des compositions pharmaceutiques comprenant les composés.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | TREM2 MODULATORS |
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