ANTIBODY CONJUGATES AND MANUFACTURE THEREOF

The present disclosure relates to conjugate compositions comprising an antibody or an antigen binding fragment, a synthetic protein, and a linker. The disclosure further relates to methods of making the conjugate compositions and to methods of using the conjugate compositions for the treatment of di...

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Hauptverfasser: ARÉVALO-RUIZ, Matilde, KREFT, Bertolt, PATTABIRAMAN, Vijaya Raghavan, MULLER, Magali, CARRALOT, Jean-Philippe, ALVAREZ SANCHEZ, Rubén
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creator ARÉVALO-RUIZ, Matilde
KREFT, Bertolt
PATTABIRAMAN, Vijaya Raghavan
MULLER, Magali
CARRALOT, Jean-Philippe
ALVAREZ SANCHEZ, Rubén
description The present disclosure relates to conjugate compositions comprising an antibody or an antigen binding fragment, a synthetic protein, and a linker. The disclosure further relates to methods of making the conjugate compositions and to methods of using the conjugate compositions for the treatment of diseases. In one aspect, the disclosure relates to the treatment of cancer using the conjugate compositions. La présente divulgation concerne des compositions conjuguées comprenant un anticorps ou un fragment liant l'antigène, une protéine synthétique et un lieur. La divulgation concerne en outre des méthodes de fabrication des compositions conjuguées et des méthodes d'utilisation des compositions conjuguées pour le traitement de maladies. Dans un aspect, la divulgation concerne le traitement du cancer à l'aide des compositions conjuguées.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title ANTIBODY CONJUGATES AND MANUFACTURE THEREOF
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