ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF
Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein- 1 (hPD-1), and immunoconjugates comprising the same. L'invention concerne des protéines d'...
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| creator | AYTON, Paul SURADE, Sachin WILSON Jr., David YAP, Kim SEN, Debasish ROZENFELD, Julia DOYLE, Anthony |
| description | Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein- 1 (hPD-1), and immunoconjugates comprising the same.
L'invention concerne des protéines d'interleukine 2 humaine (hIL2) modifiées, des molécules d'anticorps humain, ou des fragments de liaison à l'antigène associés, qui se lient de manière immunospécifique à la protéine 1 d'apoptose humaine (hPD1), et des immunoconjugués les comprenant. |
| format | Patent |
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L'invention concerne des protéines d'interleukine 2 humaine (hIL2) modifiées, des molécules d'anticorps humain, ou des fragments de liaison à l'antigène associés, qui se lient de manière immunospécifique à la protéine 1 d'apoptose humaine (hPD1), et des immunoconjugués les comprenant.</description><language>eng ; fre</language><subject>CHEMISTRY ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240201&DB=EPODOC&CC=WO&NR=2023245097A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240201&DB=EPODOC&CC=WO&NR=2023245097A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>AYTON, Paul</creatorcontrib><creatorcontrib>SURADE, Sachin</creatorcontrib><creatorcontrib>WILSON Jr., David</creatorcontrib><creatorcontrib>YAP, Kim</creatorcontrib><creatorcontrib>SEN, Debasish</creatorcontrib><creatorcontrib>ROZENFELD, Julia</creatorcontrib><creatorcontrib>DOYLE, Anthony</creatorcontrib><title>ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF</title><description>Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein- 1 (hPD-1), and immunoconjugates comprising the same.
L'invention concerne des protéines d'interleukine 2 humaine (hIL2) modifiées, des molécules d'anticorps humain, ou des fragments de liaison à l'antigène associés, qui se lient de manière immunospécifique à la protéine 1 d'apoptose humaine (hPD1), et des immunoconjugués les comprenant.</description><subject>CHEMISTRY</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHBx9Avx1A1w0TVUALGc_F0idR1DQlz9Qh1DXF0UPH10jRQ8fX1D_fyd_f28Qt2BosFAlS4KocFARoiHa5CrvxsPA2taYk5xKi-U5mZQdnMNcfbQTS3Ij08tLkhMTs1LLYkP9zcyMDI2MjE1sDR3NDYmThUA5iUsgA</recordid><startdate>20240201</startdate><enddate>20240201</enddate><creator>AYTON, Paul</creator><creator>SURADE, Sachin</creator><creator>WILSON Jr., David</creator><creator>YAP, Kim</creator><creator>SEN, Debasish</creator><creator>ROZENFELD, Julia</creator><creator>DOYLE, Anthony</creator><scope>EVB</scope></search><sort><creationdate>20240201</creationdate><title>ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF</title><author>AYTON, Paul ; SURADE, Sachin ; WILSON Jr., David ; YAP, Kim ; SEN, Debasish ; ROZENFELD, Julia ; DOYLE, Anthony</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023245097A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><toplevel>online_resources</toplevel><creatorcontrib>AYTON, Paul</creatorcontrib><creatorcontrib>SURADE, Sachin</creatorcontrib><creatorcontrib>WILSON Jr., David</creatorcontrib><creatorcontrib>YAP, Kim</creatorcontrib><creatorcontrib>SEN, Debasish</creatorcontrib><creatorcontrib>ROZENFELD, Julia</creatorcontrib><creatorcontrib>DOYLE, Anthony</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>AYTON, Paul</au><au>SURADE, Sachin</au><au>WILSON Jr., David</au><au>YAP, Kim</au><au>SEN, Debasish</au><au>ROZENFELD, Julia</au><au>DOYLE, Anthony</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF</title><date>2024-02-01</date><risdate>2024</risdate><abstract>Disclosed herein are modified human interleukin-2 (hIL-2) proteins, human antibody molecules, or antigen-binding fragments thereof, that immunospecifically bind to human programmed cell death protein- 1 (hPD-1), and immunoconjugates comprising the same.
L'invention concerne des protéines d'interleukine 2 humaine (hIL2) modifiées, des molécules d'anticorps humain, ou des fragments de liaison à l'antigène associés, qui se lient de manière immunospécifique à la protéine 1 d'apoptose humaine (hPD1), et des immunoconjugués les comprenant.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY METALLURGY ORGANIC CHEMISTRY PEPTIDES |
| title | ANTI-PD-1 ANTIBODY-ATTENUATED IL-2 IMMUNOCONJUGATES AND USES THEREOF |
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