COMPOSITIONS FOR AND METHODS OF GENE EDITING
Compositions and methods for treating a blood disorder in a subject comprising delivering a nucleic acid molecule including a nucleotide sequence encoding two to six guide RNAs (gRNAs) into a hematopoietic stem cell (HSC), a hematopoietic progenitor cell (HPC), or a population of hematopoietic stem...
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| creator | FLOREA, Michael WAGERS, Amy KARIMZADEH, Alborz |
| description | Compositions and methods for treating a blood disorder in a subject comprising delivering a nucleic acid molecule including a nucleotide sequence encoding two to six guide RNAs (gRNAs) into a hematopoietic stem cell (HSC), a hematopoietic progenitor cell (HPC), or a population of hematopoietic stem and progenitor cells (HSPCs) are described.
L'invention concerne des compositions et des méthodes de traitement d'un trouble sanguin chez un sujet, comprenant l'administration d'une molécule d'acide nucléique comprenant une séquence nucléotidique codant pour deux à six ARN guides (ARNg) dans une cellule souche hématopoïétique (CSH), une cellule progénitrice hématopoïétique (CPH), ou une population de cellules souches et progénitrices hématopoïétiques (CSPH). |
| format | Patent |
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L'invention concerne des compositions et des méthodes de traitement d'un trouble sanguin chez un sujet, comprenant l'administration d'une molécule d'acide nucléique comprenant une séquence nucléotidique codant pour deux à six ARN guides (ARNg) dans une cellule souche hématopoïétique (CSH), une cellule progénitrice hématopoïétique (CPH), ou une population de cellules souches et progénitrices hématopoïétiques (CSPH).</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231123&DB=EPODOC&CC=WO&NR=2023225409A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20231123&DB=EPODOC&CC=WO&NR=2023225409A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FLOREA, Michael</creatorcontrib><creatorcontrib>WAGERS, Amy</creatorcontrib><creatorcontrib>KARIMZADEH, Alborz</creatorcontrib><title>COMPOSITIONS FOR AND METHODS OF GENE EDITING</title><description>Compositions and methods for treating a blood disorder in a subject comprising delivering a nucleic acid molecule including a nucleotide sequence encoding two to six guide RNAs (gRNAs) into a hematopoietic stem cell (HSC), a hematopoietic progenitor cell (HPC), or a population of hematopoietic stem and progenitor cells (HSPCs) are described.
L'invention concerne des compositions et des méthodes de traitement d'un trouble sanguin chez un sujet, comprenant l'administration d'une molécule d'acide nucléique comprenant une séquence nucléotidique codant pour deux à six ARN guides (ARNg) dans une cellule souche hématopoïétique (CSH), une cellule progénitrice hématopoïétique (CPH), ou une population de cellules souches et progénitrices hématopoïétiques (CSPH).</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBx9vcN8A_2DPH09wtWcPMPUnD0c1HwdQ3x8HcJVvB3U3B39XNVcHUBKvBz52FgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGxkZGpiYGlo5GxsSpAgAe-SXs</recordid><startdate>20231123</startdate><enddate>20231123</enddate><creator>FLOREA, Michael</creator><creator>WAGERS, Amy</creator><creator>KARIMZADEH, Alborz</creator><scope>EVB</scope></search><sort><creationdate>20231123</creationdate><title>COMPOSITIONS FOR AND METHODS OF GENE EDITING</title><author>FLOREA, Michael ; WAGERS, Amy ; KARIMZADEH, Alborz</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023225409A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>FLOREA, Michael</creatorcontrib><creatorcontrib>WAGERS, Amy</creatorcontrib><creatorcontrib>KARIMZADEH, Alborz</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FLOREA, Michael</au><au>WAGERS, Amy</au><au>KARIMZADEH, Alborz</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS FOR AND METHODS OF GENE EDITING</title><date>2023-11-23</date><risdate>2023</risdate><abstract>Compositions and methods for treating a blood disorder in a subject comprising delivering a nucleic acid molecule including a nucleotide sequence encoding two to six guide RNAs (gRNAs) into a hematopoietic stem cell (HSC), a hematopoietic progenitor cell (HPC), or a population of hematopoietic stem and progenitor cells (HSPCs) are described.
L'invention concerne des compositions et des méthodes de traitement d'un trouble sanguin chez un sujet, comprenant l'administration d'une molécule d'acide nucléique comprenant une séquence nucléotidique codant pour deux à six ARN guides (ARNg) dans une cellule souche hématopoïétique (CSH), une cellule progénitrice hématopoïétique (CPH), ou une population de cellules souches et progénitrices hématopoïétiques (CSPH).</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | COMPOSITIONS FOR AND METHODS OF GENE EDITING |
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