BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR TRANSFERRIN RECEPTOR 1 (TfR1)

The present invention relates to peptide ligands, such as bicyclic peptide ligands, specific for transferrin receptor 1 (TfR1). The invention also includes pharmaceutical compositions comprising said peptide ligands and the use of said peptide ligands and pharmaceutical compositions in preventing, s...

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Bibliographische Detailangaben
Hauptverfasser:	SKYNNER, Michael, VAN RIETSCHOTEN, Katerine
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to peptide ligands, such as bicyclic peptide ligands, specific for transferrin receptor 1 (TfR1). The invention also includes pharmaceutical compositions comprising said peptide ligands and the use of said peptide ligands and pharmaceutical compositions in preventing, suppressing or treating a disease or disorder through TfR1 mediated delivery of a therapeutic agent. La présente invention concerne des ligands peptidiques, tels que des ligands peptidiques bicycliques, spécifiques du récepteur 1 de la transferrine (TfR1). L'invention concerne également des compositions pharmaceutiques comprenant lesdits ligands peptidiques et l'utilisation desdits ligands peptidiques et compositions pharmaceutiques dans la prévention, la suppression ou le traitement d'une maladie ou d'un trouble par administration médiée par TfR1 d'un agent thérapeutique.