VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE

Provided herein are proteins comprising a viral-binding domain and reagents comprising same. In some aspects, the provided proteins and reagents can be used for the purification of viral particles. In some aspects, the provided proteins and reagents improve the efficiency with which target cells can...

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Hauptverfasser: EFFENBERGER, Manuel, POLTORAK, Mateusz Pawel, FRAESSLE, Simon
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creator EFFENBERGER, Manuel
POLTORAK, Mateusz Pawel
FRAESSLE, Simon
description Provided herein are proteins comprising a viral-binding domain and reagents comprising same. In some aspects, the provided proteins and reagents can be used for the purification of viral particles. In some aspects, the provided proteins and reagents improve the efficiency with which target cells can be transduced. Also provided herein are methods using the provided proteins and reagents, including for purifying viral particles or for transducing cells. Related kits and articles of manufacture are also provided. L'invention concerne des protéines comprenant un domaine de liaison virale et des réactifs les comprenant. Dans certains aspects, les protéines et les réactifs selon l'invention peuvent être utilisés pour la purification de particules virales. Dans certains aspects, les protéines et les réactifs selon l'invention améliorent l'efficacité avec laquelle des cellules cibles peuvent être transduites. L'invention concerne également des méthodes faisant appel aux protéines et aux réactifs selon l'invention, notamment pour la purification de particules virales ou la transduction de cellules. L'invention concerne également des kits et des articles manufacturés associés.
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L'invention concerne également des méthodes faisant appel aux protéines et aux réactifs selon l'invention, notamment pour la purification de particules virales ou la transduction de cellules. 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L'invention concerne également des méthodes faisant appel aux protéines et aux réactifs selon l'invention, notamment pour la purification de particules virales ou la transduction de cellules. 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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PERFORMING OPERATIONS
PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SEPARATION
SPIRITS
TRANSPORTING
VINEGAR
WINE
title VIRAL-BINDING PROTEIN AND RELATED REAGENTS, ARTICLES, AND METHODS OF USE
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