PROTECTING OLIGONUCLEOTIDES FOR CRISPR GUIDE RNA

Protecting oligonucleotides are provided. Protecting oligonucleotides with 5' and/or 3' conjugated moieties are provided. Protecting oligonucleotides with chemical modifications are provided. Methods of using the protecting oligonucleotides for genome editing with a CRISPR nuclease and kit...

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Bibliographische Detailangaben
Hauptverfasser: SONTHEIMER, Erik Joseph, ZHANG, Han, KHVOROVA, Anastasia, WATTS, Jonathan Kenneth
Format: Patent
Sprache:eng ; fre
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