PYRIDO[3,2-D]PYRIMIDINES AS HPK1 INHIBITORS

Pyrido[3,2-d]pyrimidine compounds are provided that are potent HPK1 inhibitors that are useful to treat or prevent cancer and/or inflammatory and/or autoimmune diseases or symptoms thereof in mammals, particularly humans. The compounds disclosed herein have a chemical structure of the general formul...

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Hauptverfasser:	CUMMINGS, James, NEAGU, Constantin, FRIIS, Emily, WANG, Yanping, LI, Bin, TOURE, Momar, CHEKLER, Eugene, JOHNSON, Theresa
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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