ANTI-INFLAMMATORY SIGLEC-6 PROTEINS AND METHODS OF MAKING AND USING SAME

The invention relates generally to proteins comprising a recombinant Siglec-6 extracellular domain (ECD), or a functional fragment or variant thereof, optionally containing a mutation that reduces sialic acid binding activity, and conjugated to multiple serum half-life enhancers, e.g., an immunoglob...

Ausführliche Beschreibung

Bibliographische Detailangaben

Hauptverfasser:	CAO, Lizhi, PENG, Li, NERLE, Sujata B
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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