STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF

The invention provides novel modulators of STING (Stimulator of Interferon Genes) and pharmaceutical compositions thereof, as well as methods of their preparation and use, in therapy of various diseases and conditions, such as cancer, infectious and autoimmune diseases or disorders. L'invention...

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Hauptverfasser: YU, Xiang, WANG, Legang, ZHAO, Jean, WANG, Qi, XU, Musheng, SUN, Yina, LI, Xiuyun, CHENG, Huimin, CHEN, Yayu
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creator YU, Xiang
WANG, Legang
ZHAO, Jean
WANG, Qi
XU, Musheng
SUN, Yina
LI, Xiuyun
CHENG, Huimin
CHEN, Yayu
description The invention provides novel modulators of STING (Stimulator of Interferon Genes) and pharmaceutical compositions thereof, as well as methods of their preparation and use, in therapy of various diseases and conditions, such as cancer, infectious and autoimmune diseases or disorders. L'invention concerne de nouveaux modulateurs de STING (stimulateur de gènes d'interféron) et des compositions pharmaceutiques de ceux-ci, ainsi que des méthodes de préparation et d'utilisation de ceux-ci, dans la thérapie de diverses maladies et affections, telles que le cancer, des maladies ou des troubles infectieux et auto-immuns.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title STIMULATOR OF INTERFERON GENES (STING) MODULATORS, AND COMPOSITIONS AND METHODS THEREOF
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