LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF

The present invention relates to a liquid botulinum toxin formulation comprising: (i) botulinum toxin, (ii) a stabilizing protein such as human serum albumin, (iii) a chelating agent (e.g., EDTA) or phosphate, and optionally (iv) a salt of calcium, magnesium or zinc, (v) a tonicity agent and/or (vi)...

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Hauptverfasser: TAYLOR, Harold V, KÜHBACH, Katja, JATZKE, Claudia, FINK, Klaus, EISELE, Karl-Heinz
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creator TAYLOR, Harold V
KÜHBACH, Katja
JATZKE, Claudia
FINK, Klaus
EISELE, Karl-Heinz
description The present invention relates to a liquid botulinum toxin formulation comprising: (i) botulinum toxin, (ii) a stabilizing protein such as human serum albumin, (iii) a chelating agent (e.g., EDTA) or phosphate, and optionally (iv) a salt of calcium, magnesium or zinc, (v) a tonicity agent and/or (vi) a buffering agent. In addition, the present invention relates to the use of the liquid botulinum toxin formulation for therapeutic and cosmetic treatments. La présente invention concerne une formulation de toxine botulique liquide comprenant : (i) une toxine botulinique, (ii) une protéine de stabilisation telle que l'albumine sérique humaine, (iii) un agent chélatant (par exemple, EDTA) ou un phosphate, et éventuellement (iv) un sel de calcium, de magnésium ou de zinc, (v) un agent de tonicité et/ou (vi) un agent tampon. De plus, la présente invention concerne l'utilisation de la formulation de toxine botulique liquide pour des traitements thérapeutiques et cosmétiques.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title LIQUID BOTULINUM TOXIN FORMULATION AND USE THEREOF
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