APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS
Provided is an application of CD45 as a biomarker in screening the effectiveness of a CD26 antibody or a derivative thereof in treating tumors in a test subject. Specifically, when CD45 is not expressed or has low expression, determining that the treatment of the test subject who has received a CD26...
Gespeichert in:
Hauptverfasser: | , , , |
---|---|
Format: | Patent |
Sprache: | chi ; eng ; fre |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | |
---|---|
container_issue | |
container_start_page | |
container_title | |
container_volume | |
creator | HANG, Jianhua CAO, Peipei GE, Chennan MA, Bruce Yong |
description | Provided is an application of CD45 as a biomarker in screening the effectiveness of a CD26 antibody or a derivative thereof in treating tumors in a test subject. Specifically, when CD45 is not expressed or has low expression, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is effective or has a high probability of being effective; and when CD45 expression is high or relatively high, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is ineffective or has a high probability of being ineffective. By filtering-out a biomarker capable of effectively screening the tumor treatment effectiveness of a CD26 antibody or derivative thereof, it is possible to greatly improve the precision and effectiveness of tumor treatment by the CD26 antibody or derivative thereof, thus improving the clinical benefit to the patient; it has been found that CD26 acts as a new mechanism for treatment effectiveness and prec |
format | Patent |
fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2023143245A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2023143245A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2023143245A13</originalsourceid><addsrcrecordid>eNqNjLEKwjAURbs4iPoPD5wFm1b3NH2xD21SXmLFqRSJk2ih_oE_bgRxdrpwOOdOk5dsmgMp6ckasBpUmW9AOijI1pL3yEAGnGJEQ2YHqDUqTy0adA6kKaFhVOR-tdhG6qmw5RksQ4lMrfwE4CtkjE7884yRxTt_rC27eTK59rcxLL47S5YavapWYXh0YRz6S7iHZ3eyYi2yNM9EvpFp9p_1BqW9PVM</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS</title><source>esp@cenet</source><creator>HANG, Jianhua ; CAO, Peipei ; GE, Chennan ; MA, Bruce Yong</creator><creatorcontrib>HANG, Jianhua ; CAO, Peipei ; GE, Chennan ; MA, Bruce Yong</creatorcontrib><description>Provided is an application of CD45 as a biomarker in screening the effectiveness of a CD26 antibody or a derivative thereof in treating tumors in a test subject. Specifically, when CD45 is not expressed or has low expression, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is effective or has a high probability of being effective; and when CD45 expression is high or relatively high, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is ineffective or has a high probability of being ineffective. By filtering-out a biomarker capable of effectively screening the tumor treatment effectiveness of a CD26 antibody or derivative thereof, it is possible to greatly improve the precision and effectiveness of tumor treatment by the CD26 antibody or derivative thereof, thus improving the clinical benefit to the patient; it has been found that CD26 acts as a new mechanism for treatment effectiveness and prec</description><language>chi ; eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&CC=WO&NR=2023143245A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25569,76552</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230803&DB=EPODOC&CC=WO&NR=2023143245A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>HANG, Jianhua</creatorcontrib><creatorcontrib>CAO, Peipei</creatorcontrib><creatorcontrib>GE, Chennan</creatorcontrib><creatorcontrib>MA, Bruce Yong</creatorcontrib><title>APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS</title><description>Provided is an application of CD45 as a biomarker in screening the effectiveness of a CD26 antibody or a derivative thereof in treating tumors in a test subject. Specifically, when CD45 is not expressed or has low expression, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is effective or has a high probability of being effective; and when CD45 expression is high or relatively high, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is ineffective or has a high probability of being ineffective. By filtering-out a biomarker capable of effectively screening the tumor treatment effectiveness of a CD26 antibody or derivative thereof, it is possible to greatly improve the precision and effectiveness of tumor treatment by the CD26 antibody or derivative thereof, thus improving the clinical benefit to the patient; it has been found that CD26 acts as a new mechanism for treatment effectiveness and prec</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwjAURbs4iPoPD5wFm1b3NH2xD21SXmLFqRSJk2ih_oE_bgRxdrpwOOdOk5dsmgMp6ckasBpUmW9AOijI1pL3yEAGnGJEQ2YHqDUqTy0adA6kKaFhVOR-tdhG6qmw5RksQ4lMrfwE4CtkjE7884yRxTt_rC27eTK59rcxLL47S5YavapWYXh0YRz6S7iHZ3eyYi2yNM9EvpFp9p_1BqW9PVM</recordid><startdate>20230803</startdate><enddate>20230803</enddate><creator>HANG, Jianhua</creator><creator>CAO, Peipei</creator><creator>GE, Chennan</creator><creator>MA, Bruce Yong</creator><scope>EVB</scope></search><sort><creationdate>20230803</creationdate><title>APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS</title><author>HANG, Jianhua ; CAO, Peipei ; GE, Chennan ; MA, Bruce Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023143245A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng ; fre</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>HANG, Jianhua</creatorcontrib><creatorcontrib>CAO, Peipei</creatorcontrib><creatorcontrib>GE, Chennan</creatorcontrib><creatorcontrib>MA, Bruce Yong</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>HANG, Jianhua</au><au>CAO, Peipei</au><au>GE, Chennan</au><au>MA, Bruce Yong</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS</title><date>2023-08-03</date><risdate>2023</risdate><abstract>Provided is an application of CD45 as a biomarker in screening the effectiveness of a CD26 antibody or a derivative thereof in treating tumors in a test subject. Specifically, when CD45 is not expressed or has low expression, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is effective or has a high probability of being effective; and when CD45 expression is high or relatively high, determining that the treatment of the test subject who has received a CD26 antibody or a derivative thereof is ineffective or has a high probability of being ineffective. By filtering-out a biomarker capable of effectively screening the tumor treatment effectiveness of a CD26 antibody or derivative thereof, it is possible to greatly improve the precision and effectiveness of tumor treatment by the CD26 antibody or derivative thereof, thus improving the clinical benefit to the patient; it has been found that CD26 acts as a new mechanism for treatment effectiveness and prec</abstract><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | |
ispartof | |
issn | |
language | chi ; eng ; fre |
recordid | cdi_epo_espacenet_WO2023143245A1 |
source | esp@cenet |
subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | APPLICATION OF CD45 AS BIOMARKER IN SCREENING EFFECTIVENESS AND PRECISION OF CD26 ANTIBODY OR DERIVATIVE THEREOF IN TREATING TUMORS |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-11T14%3A56%3A59IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=HANG,%20Jianhua&rft.date=2023-08-03&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2023143245A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |