(4-PIPERAZIN-1YL)-4-ALKYL-PHTHALAZIN-1(2H)-ONE COMPOUNDS AS PARP7 INHIBITORS

The present invention provides compounds of formula (I) as poly(ADP-ribose) polymerase 7 (PARP7) inhibitors, methods of preparing them, pharmaceutical compositions containing them and their use in methods of treatment, prevention and/or amelioration of diseases or disorders involving PARP7. La prése...

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Bibliographische Detailangaben
Hauptverfasser:	VAKKALANKA, Swaroop Kumar Venkata Satya, BABU, Govindarajulu, BHUNIYA, Debnath, ELESWARAPU, Venkata Satyanarayana
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (I) as poly(ADP-ribose) polymerase 7 (PARP7) inhibitors, methods of preparing them, pharmaceutical compositions containing them and their use in methods of treatment, prevention and/or amelioration of diseases or disorders involving PARP7. La présente invention concerne des composés de formule (I) utilisés comme inhibiteurs de poly(ADP-ribose) polymérase 7 (PARP7), des méthodes de préparation de ceux-ci, des compositions pharmaceutiques les contenant et leur utilisation dans des méthodes de traitement, de prévention et/ou d'atténuation de maladies ou de troubles impliquant PARP7.