METHOD FOR PREPARING OUTER MEMBRANE VESICLES

The present invention relates to Shigella outer membrane vesicles comprising at least one heterologous O-antigen, a recombinant Shigella bacterium comprising at least one heterologous O-antigen, methods for preparing the outer membrane vesicles or recombinant Shigella bacterium, plasmids for use in...

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Hauptverfasser: MICOLI, Francesca, SAUL, Allan James, GASPERINI, Gianmarco, CITIULO, Francesco, MARTIN, Laura Bartle
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creator MICOLI, Francesca
SAUL, Allan James
GASPERINI, Gianmarco
CITIULO, Francesco
MARTIN, Laura Bartle
description The present invention relates to Shigella outer membrane vesicles comprising at least one heterologous O-antigen, a recombinant Shigella bacterium comprising at least one heterologous O-antigen, methods for preparing the outer membrane vesicles or recombinant Shigella bacterium, plasmids for use in the methods, immunogenic compositions, vaccines and methods of treatment. La présente invention concerne des vésicules de membrane externe de Shigella comprenant au moins un antigène O hétérologue, une bactérie Shigella recombinante comprenant au moins un antigène O hétérologue, des procédés de préparation des vésicules de membrane externe ou de la bactérie Shigella recombinante, des plasmides destinés à être utilisés dans les procédés, des compositions immunogènes, des vaccins et des méthodes de traitement.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title METHOD FOR PREPARING OUTER MEMBRANE VESICLES
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