FIVE- AND SIX-MEMBERED COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION AND USE THEREOF

A five- and six-membered compound, and a preparation method therefor and a pharmaceutical composition and the use thereof. The five- and six-membered compound is a compound as shown in formula I, II or III. The compound has an inhibitory effect on FLT3 and/or IRAK4. L'invention concerne un comp...

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Hauptverfasser:	XU, Rui, XIANG, Michael, WU, Lei, TONG, Mixue, XIANG, Camille, YANG, Rui, YANG, Gang, XIANG, Jason Shaoyun, WANG, Suyue, ZHANG, Qiang, LIU, Yuxin
Format:	Patent
Sprache:	chi ; eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	XU, Rui XIANG, Michael WU, Lei TONG, Mixue XIANG, Camille YANG, Rui YANG, Gang XIANG, Jason Shaoyun WANG, Suyue ZHANG, Qiang LIU, Yuxin
description	A five- and six-membered compound, and a preparation method therefor and a pharmaceutical composition and the use thereof. The five- and six-membered compound is a compound as shown in formula I, II or III. The compound has an inhibitory effect on FLT3 and/or IRAK4. L'invention concerne un composé à cinq et six chaînons, son procédé de préparation et une composition pharmaceutique et son utilisation. Le composé à cinq et six chaînons est un composé tel que représenté dans la formule I, II ou III. Le composé a un effet inhibiteur sur FLT3 et/ou IRAK4. 一种五元并六元化合物、制备方法、药物组合物和应用。五元并六元化合物为如式I、II或III所示化合物。化合物对FLT3和/或IRAK4具有抑制效果。
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subjects	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	FIVE- AND SIX-MEMBERED COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION AND USE THEREOF
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