METHOD AND APPARATUS FOR STERILE AND NONINVASIVE MEASUREMENTS OF SUBSTANCES IN BIOREACTORS AND OTHER STERILE ENVIRONMENTS
The present invention provides for systems and method for noninvasive measurement and monitoring of cell culture parameters including dissolved oxygen (DO), dissolved carbon dioxide (DCO2), and pH wherein there is no direct contact with the cell culture environment which is achieved by conducting th...
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| creator | RAO, Govind KUMAR, Vikash TOLOSA, Michael RAHMATNEJAD, Vida GE, Xudong |
| description | The present invention provides for systems and method for noninvasive measurement and monitoring of cell culture parameters including dissolved oxygen (DO), dissolved carbon dioxide (DCO2), and pH wherein there is no direct contact with the cell culture environment which is achieved by conducting the measurements and monitoring on the outside of the bioreactor through semi-permeable membranes incorporated into the system to enhance the process and eliminate the risk of contamination associated with invasive sensors.
La présente invention concerne des systèmes et des procédés de mesure et de suivi non invasifs de paramètres de culture cellulaire, notamment l'oxygène dissous (DO), le dioxyde de carbone dissous (DCO2) et le pH, sans contact direct avec l'environnement de culture cellulaire. Les mesures et le suivi sont effectués à l'extérieur du bioréacteur, à travers des membranes semi-perméables incorporées au système, afin d'améliorer le processus et d'éliminer le risque de contamination associé aux capteurs invasifs. |
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La présente invention concerne des systèmes et des procédés de mesure et de suivi non invasifs de paramètres de culture cellulaire, notamment l'oxygène dissous (DO), le dioxyde de carbone dissous (DCO2) et le pH, sans contact direct avec l'environnement de culture cellulaire. Les mesures et le suivi sont effectués à l'extérieur du bioréacteur, à travers des membranes semi-perméables incorporées au système, afin d'améliorer le processus et d'éliminer le risque de contamination associé aux capteurs invasifs.</description><language>eng ; fre</language><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY ; BEER ; BIOCHEMISTRY ; CHEMISTRY ; ENZYMOLOGY ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230615&DB=EPODOC&CC=WO&NR=2023107879A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230615&DB=EPODOC&CC=WO&NR=2023107879A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAO, Govind</creatorcontrib><creatorcontrib>KUMAR, Vikash</creatorcontrib><creatorcontrib>TOLOSA, Michael</creatorcontrib><creatorcontrib>RAHMATNEJAD, Vida</creatorcontrib><creatorcontrib>GE, Xudong</creatorcontrib><title>METHOD AND APPARATUS FOR STERILE AND NONINVASIVE MEASUREMENTS OF SUBSTANCES IN BIOREACTORS AND OTHER STERILE ENVIRONMENTS</title><description>The present invention provides for systems and method for noninvasive measurement and monitoring of cell culture parameters including dissolved oxygen (DO), dissolved carbon dioxide (DCO2), and pH wherein there is no direct contact with the cell culture environment which is achieved by conducting the measurements and monitoring on the outside of the bioreactor through semi-permeable membranes incorporated into the system to enhance the process and eliminate the risk of contamination associated with invasive sensors.
La présente invention concerne des systèmes et des procédés de mesure et de suivi non invasifs de paramètres de culture cellulaire, notamment l'oxygène dissous (DO), le dioxyde de carbone dissous (DCO2) et le pH, sans contact direct avec l'environnement de culture cellulaire. Les mesures et le suivi sont effectués à l'extérieur du bioréacteur, à travers des membranes semi-perméables incorporées au système, afin d'améliorer le processus et d'éliminer le risque de contamination associé aux capteurs invasifs.</description><subject>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</subject><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>ENZYMOLOGY</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwkAQRNNYiPoPC9aCSYpouYkbcmB2w-0mliHIWYkKsfHvlSDYWgxTzHszj141WSUHQP6kadCjtQqleFAj7440LSzsuEN1HUFNqK2nmtgUpARtczXkghQcQ-7EExYmXidTrKLfF3HnvPDkLqPZZbiOYfXtRbQuyYpqEx73PoyP4Rxu4dmfJNkmabzNdtke4_Q_6g3z0zu3</recordid><startdate>20230615</startdate><enddate>20230615</enddate><creator>RAO, Govind</creator><creator>KUMAR, Vikash</creator><creator>TOLOSA, Michael</creator><creator>RAHMATNEJAD, Vida</creator><creator>GE, Xudong</creator><scope>EVB</scope></search><sort><creationdate>20230615</creationdate><title>METHOD AND APPARATUS FOR STERILE AND NONINVASIVE MEASUREMENTS OF SUBSTANCES IN BIOREACTORS AND OTHER STERILE ENVIRONMENTS</title><author>RAO, Govind ; KUMAR, Vikash ; TOLOSA, Michael ; RAHMATNEJAD, Vida ; GE, Xudong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023107879A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY</topic><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>ENZYMOLOGY</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>RAO, Govind</creatorcontrib><creatorcontrib>KUMAR, Vikash</creatorcontrib><creatorcontrib>TOLOSA, Michael</creatorcontrib><creatorcontrib>RAHMATNEJAD, Vida</creatorcontrib><creatorcontrib>GE, Xudong</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAO, Govind</au><au>KUMAR, Vikash</au><au>TOLOSA, Michael</au><au>RAHMATNEJAD, Vida</au><au>GE, Xudong</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD AND APPARATUS FOR STERILE AND NONINVASIVE MEASUREMENTS OF SUBSTANCES IN BIOREACTORS AND OTHER STERILE ENVIRONMENTS</title><date>2023-06-15</date><risdate>2023</risdate><abstract>The present invention provides for systems and method for noninvasive measurement and monitoring of cell culture parameters including dissolved oxygen (DO), dissolved carbon dioxide (DCO2), and pH wherein there is no direct contact with the cell culture environment which is achieved by conducting the measurements and monitoring on the outside of the bioreactor through semi-permeable membranes incorporated into the system to enhance the process and eliminate the risk of contamination associated with invasive sensors.
La présente invention concerne des systèmes et des procédés de mesure et de suivi non invasifs de paramètres de culture cellulaire, notamment l'oxygène dissous (DO), le dioxyde de carbone dissous (DCO2) et le pH, sans contact direct avec l'environnement de culture cellulaire. Les mesures et le suivi sont effectués à l'extérieur du bioréacteur, à travers des membranes semi-perméables incorporées au système, afin d'améliorer le processus et d'éliminer le risque de contamination associé aux capteurs invasifs.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING SPIRITS VINEGAR WINE |
| title | METHOD AND APPARATUS FOR STERILE AND NONINVASIVE MEASUREMENTS OF SUBSTANCES IN BIOREACTORS AND OTHER STERILE ENVIRONMENTS |
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