SINGLE DOMAIN ANTIBODIES FOR PREVENTION OF CLOSTRIDIUM DIFFICILE INFECTION
The present disclosure relates to single domain antibodies which binds to Clostridium difficile toxin B and their use in the treatment and prevention of Clostridium difficile infection. Further disclosed are nucleic acids and vectors encoding the single domain antibodies, host cells for expression o...
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| creator | LAUSTSEN, Mads Aage THRANE, Sandra Wingaard LAUSTSEN, Andreas Hougaard RODRIGUEZ-RODRIGUEZ, Everardo |
| description | The present disclosure relates to single domain antibodies which binds to Clostridium difficile toxin B and their use in the treatment and prevention of Clostridium difficile infection. Further disclosed are nucleic acids and vectors encoding the single domain antibodies, host cells for expression of the single domain antibodies, methods of manufacture and compositions.
La présente invention concerne des anticorps à domaine unique qui se lient à la toxine B du Clostridium difficile et leur utilisation dans le traitement et la prévention d'une infection à Clostridium difficile. L'invention concerne en outre des acides nucléiques et des vecteurs codant pour les anticorps à domaine unique, des cellules hôtes pour l'expression des anticorps à domaine unique, des procédés de fabrication et des compositions. |
| format | Patent |
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La présente invention concerne des anticorps à domaine unique qui se lient à la toxine B du Clostridium difficile et leur utilisation dans le traitement et la prévention d'une infection à Clostridium difficile. L'invention concerne en outre des acides nucléiques et des vecteurs codant pour les anticorps à domaine unique, des cellules hôtes pour l'expression des anticorps à domaine unique, des procédés de fabrication et des compositions.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; TESTING</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230608&DB=EPODOC&CC=WO&NR=2023099711A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230608&DB=EPODOC&CC=WO&NR=2023099711A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LAUSTSEN, Mads Aage</creatorcontrib><creatorcontrib>THRANE, Sandra Wingaard</creatorcontrib><creatorcontrib>LAUSTSEN, Andreas Hougaard</creatorcontrib><creatorcontrib>RODRIGUEZ-RODRIGUEZ, Everardo</creatorcontrib><title>SINGLE DOMAIN ANTIBODIES FOR PREVENTION OF CLOSTRIDIUM DIFFICILE INFECTION</title><description>The present disclosure relates to single domain antibodies which binds to Clostridium difficile toxin B and their use in the treatment and prevention of Clostridium difficile infection. Further disclosed are nucleic acids and vectors encoding the single domain antibodies, host cells for expression of the single domain antibodies, methods of manufacture and compositions.
La présente invention concerne des anticorps à domaine unique qui se lient à la toxine B du Clostridium difficile et leur utilisation dans le traitement et la prévention d'une infection à Clostridium difficile. L'invention concerne en outre des acides nucléiques et des vecteurs codant pour les anticorps à domaine unique, des cellules hôtes pour l'expression des anticorps à domaine unique, des procédés de fabrication et des compositions.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZPAK9vRz93FVcPH3dfT0U3D0C_F08nfxdA1WcPMPUggIcg1zBQr5-yn4uyk4-_gHhwR5uniG-iq4eLq5eTp7AnV6-rm5OoOU8DCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSS-HB_IwMjYwNLS3NDQ0cjY-JUAQAi6C52</recordid><startdate>20230608</startdate><enddate>20230608</enddate><creator>LAUSTSEN, Mads Aage</creator><creator>THRANE, Sandra Wingaard</creator><creator>LAUSTSEN, Andreas Hougaard</creator><creator>RODRIGUEZ-RODRIGUEZ, Everardo</creator><scope>EVB</scope></search><sort><creationdate>20230608</creationdate><title>SINGLE DOMAIN ANTIBODIES FOR PREVENTION OF CLOSTRIDIUM DIFFICILE INFECTION</title><author>LAUSTSEN, Mads Aage ; THRANE, Sandra Wingaard ; LAUSTSEN, Andreas Hougaard ; RODRIGUEZ-RODRIGUEZ, Everardo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023099711A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>LAUSTSEN, Mads Aage</creatorcontrib><creatorcontrib>THRANE, Sandra Wingaard</creatorcontrib><creatorcontrib>LAUSTSEN, Andreas Hougaard</creatorcontrib><creatorcontrib>RODRIGUEZ-RODRIGUEZ, Everardo</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LAUSTSEN, Mads Aage</au><au>THRANE, Sandra Wingaard</au><au>LAUSTSEN, Andreas Hougaard</au><au>RODRIGUEZ-RODRIGUEZ, Everardo</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SINGLE DOMAIN ANTIBODIES FOR PREVENTION OF CLOSTRIDIUM DIFFICILE INFECTION</title><date>2023-06-08</date><risdate>2023</risdate><abstract>The present disclosure relates to single domain antibodies which binds to Clostridium difficile toxin B and their use in the treatment and prevention of Clostridium difficile infection. Further disclosed are nucleic acids and vectors encoding the single domain antibodies, host cells for expression of the single domain antibodies, methods of manufacture and compositions.
La présente invention concerne des anticorps à domaine unique qui se lient à la toxine B du Clostridium difficile et leur utilisation dans le traitement et la prévention d'une infection à Clostridium difficile. L'invention concerne en outre des acides nucléiques et des vecteurs codant pour les anticorps à domaine unique, des cellules hôtes pour l'expression des anticorps à domaine unique, des procédés de fabrication et des compositions.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS TESTING |
| title | SINGLE DOMAIN ANTIBODIES FOR PREVENTION OF CLOSTRIDIUM DIFFICILE INFECTION |
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