EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS
Disclosed herein are reduced viscosity liquid formulations comprising a protein, optionally a therapeutic protein or more optionally a therapeutic antibody, and excipient compounds, optionally a lyo-enhancing excipient or more optionally caffeine. Further disclosed are methods of reducing the viscos...
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creator | WUTHRICH, Philip NAIK, Subhashchandra ZENG, Yuhong TRAN, Timothy MAHONEY, Robert P |
description | Disclosed herein are reduced viscosity liquid formulations comprising a protein, optionally a therapeutic protein or more optionally a therapeutic antibody, and excipient compounds, optionally a lyo-enhancing excipient or more optionally caffeine. Further disclosed are methods of reducing the viscosity of a liquid formulation comprising a protein, methods of treatment, and methods of improving protein processing.
L'invention concerne des formulations liquides à viscosité réduite comprenant une protéine, facultativement une protéine thérapeutique ou encore un anticorps thérapeutique, et des composés excipients, facultativement un excipient améliorant la lyophilisation ou encore de la caféine. L'invention concerne en outre des méthodes de réduction de la viscosité d'une formulation liquide comprenant une protéine, des méthodes de traitement et des méthodes d'amélioration du traitement des protéines. |
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L'invention concerne des formulations liquides à viscosité réduite comprenant une protéine, facultativement une protéine thérapeutique ou encore un anticorps thérapeutique, et des composés excipients, facultativement un excipient améliorant la lyophilisation ou encore de la caféine. L'invention concerne en outre des méthodes de réduction de la viscosité d'une formulation liquide comprenant une protéine, des méthodes de traitement et des méthodes d'amélioration du traitement des protéines.</description><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230525&DB=EPODOC&CC=WO&NR=2023091370A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230525&DB=EPODOC&CC=WO&NR=2023091370A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WUTHRICH, Philip</creatorcontrib><creatorcontrib>NAIK, Subhashchandra</creatorcontrib><creatorcontrib>ZENG, Yuhong</creatorcontrib><creatorcontrib>TRAN, Timothy</creatorcontrib><creatorcontrib>MAHONEY, Robert P</creatorcontrib><title>EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS</title><description>Disclosed herein are reduced viscosity liquid formulations comprising a protein, optionally a therapeutic protein or more optionally a therapeutic antibody, and excipient compounds, optionally a lyo-enhancing excipient or more optionally caffeine. Further disclosed are methods of reducing the viscosity of a liquid formulation comprising a protein, methods of treatment, and methods of improving protein processing.
L'invention concerne des formulations liquides à viscosité réduite comprenant une protéine, facultativement une protéine thérapeutique ou encore un anticorps thérapeutique, et des composés excipients, facultativement un excipient améliorant la lyophilisation ou encore de la caféine. L'invention concerne en outre des méthodes de réduction de la viscosité d'une formulation liquide comprenant une protéine, des méthodes de traitement et des méthodes d'amélioration du traitement des protéines.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNB3jXD2DPB09QtRcPb3DfAP9XMJVnDzD1Jw8vQP8PeJ9HUNAnF9Q30cQzz9_YJ5GFjTEnOKU3mhNDeDsptriLOHbmpBfnxqcUFicmpeakl8uL-RgZGxgaWhsbmBo6ExcaoA2DUnaQ</recordid><startdate>20230525</startdate><enddate>20230525</enddate><creator>WUTHRICH, Philip</creator><creator>NAIK, Subhashchandra</creator><creator>ZENG, Yuhong</creator><creator>TRAN, Timothy</creator><creator>MAHONEY, Robert P</creator><scope>EVB</scope></search><sort><creationdate>20230525</creationdate><title>EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS</title><author>WUTHRICH, Philip ; NAIK, Subhashchandra ; ZENG, Yuhong ; TRAN, Timothy ; MAHONEY, Robert P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023091370A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>WUTHRICH, Philip</creatorcontrib><creatorcontrib>NAIK, Subhashchandra</creatorcontrib><creatorcontrib>ZENG, Yuhong</creatorcontrib><creatorcontrib>TRAN, Timothy</creatorcontrib><creatorcontrib>MAHONEY, Robert P</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>WUTHRICH, Philip</au><au>NAIK, Subhashchandra</au><au>ZENG, Yuhong</au><au>TRAN, Timothy</au><au>MAHONEY, Robert P</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS</title><date>2023-05-25</date><risdate>2023</risdate><abstract>Disclosed herein are reduced viscosity liquid formulations comprising a protein, optionally a therapeutic protein or more optionally a therapeutic antibody, and excipient compounds, optionally a lyo-enhancing excipient or more optionally caffeine. Further disclosed are methods of reducing the viscosity of a liquid formulation comprising a protein, methods of treatment, and methods of improving protein processing.
L'invention concerne des formulations liquides à viscosité réduite comprenant une protéine, facultativement une protéine thérapeutique ou encore un anticorps thérapeutique, et des composés excipients, facultativement un excipient améliorant la lyophilisation ou encore de la caféine. L'invention concerne en outre des méthodes de réduction de la viscosité d'une formulation liquide comprenant une protéine, des méthodes de traitement et des méthodes d'amélioration du traitement des protéines.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | EXCIPIENT COMPOUNDS FOR BIOPOLYMER FORMULATIONS |
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