MOLECULES THAT BIND TO PROTOGENIN (PRTG) POLYPEPTIDES

This document provides methods and materials involved in binding a binder (e.g., an antibody, antigen binding fragment, antibody domain, CAR, cell engager, and/or ADC) to a PRTG polypeptide. For example, binders (e.g., antibodies, antigen binding fragments, antibody domains, CARs, cell engagers, and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	CHEN, Chuan, TAYLOR, Michael D, DIMITROV, Dimiter Stanchev, SUN, Zehua, LI, Wei, VISVANATHAN, Abhirami, SAULNIER, Olivier
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This document provides methods and materials involved in binding a binder (e.g., an antibody, antigen binding fragment, antibody domain, CAR, cell engager, and/or ADC) to a PRTG polypeptide. For example, binders (e.g., antibodies, antigen binding fragments, antibody domains, CARs, cell engagers, and/or ADCs) that bind to a PRTG polypeptide and methods and materials for using one or more such binding molecules to treat a mammal (e.g., a human) having cancer are provided. Ce document concerne des procédés et des matériaux impliqués dans la liaison d'un liant (par exemple, un anticorps, un fragment de liaison à l'antigène, un domaine d'anticorps, un CAR, un engageur de cellule et/ou un ADC) à un polypeptide PRTG. Par exemple, l'invention concerne des liants (par exemple, des anticorps, des fragments de liaison à l'antigène, des domaines d'anticorps, des CAR, des engageurs de cellules et/ou des ADC) qui se lient à un polypeptide PRTG et des procédés et des matériaux pour utiliser une ou plusieurs de ces molécules de liaison pour traiter un mammifère (par exemple, un être humain) ayant un cancer.