PHARMACEUTICAL FORMULATIONS COMPRISING ANTI-CORONAVIRUS S PROTEIN ANTIBODIES AND USES THEREOF

PHARMACEUTICAL FORMULATIONS COMPRISING ANTI-CORONAVIRUS S PROTEIN ANTIBODIES AND USES THEREOF

The present disclosure is directed to pharmaceutical formulations comprising antibodies, and antigen binding fragments thereof, having binding specificity for the S protein of coronaviruses (CoV-S). Other embodiments of the disclosure include the use of pharmaceutical formulations for the diagnosis,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MANNING, Mark, DABORA, Rebecca, HOLCOLM, Ryan, RATNASWAMY, Gayathri, MARTIN-MOE, Sheryl
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present disclosure is directed to pharmaceutical formulations comprising antibodies, and antigen binding fragments thereof, having binding specificity for the S protein of coronaviruses (CoV-S). Other embodiments of the disclosure include the use of pharmaceutical formulations for the diagnosis, assessment, and treatment of diseases and disorders associated with coronaviruses, or the S protein thereof, and conditions where neutralization or inhibition of coronaviruses, or the S protein thereof, would be therapeutically and/or prophylactically beneficial. La présente invention concerne des formulations pharmaceutiques comprenant des anticorps, et des fragments de liaison à l'antigène de ceux-ci, ayant une spécificité de liaison pour la protéine S des coronavirus (CoV-S). D'autres modes de réalisation de la divulgation comprennent l'utilisation de formulations pour le diagnostic, l'évaluation et le traitement de maladies et de troubles associés à des coronavirus, ou à la protéine S correspondante, et des conditions dans lesquelles la neutralisation ou l'inhibition des coronavirus, ou de la protéine S correspondante, serait bénéfique sur le plan thérapeutique et/ou prophylactique.