FORMATE DEHYDROGENASE VARIANTS AND METHODS OF USE

The disclosure provides polypeptides and encoding nucleic acids of engineered formate dehydrogenases. The disclosure also provides cells expressing an engineered formate dehydrogenase. The disclosure further provides methods for producing a bioderived compound comprising culturing cells expressing a...

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Bibliographische Detailangaben
Hauptverfasser:	NAPOLITANO, Michael Gregory, WARNER, Joseph Roy, PRAVESCHOTINUNT, Pichet, SCHMIDT, Nathan, COLQUITT, Justin Robert, SHAH, Amit Mahendra
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The disclosure provides polypeptides and encoding nucleic acids of engineered formate dehydrogenases. The disclosure also provides cells expressing an engineered formate dehydrogenase. The disclosure further provides methods for producing a bioderived compound comprising culturing cells expressing an engineered formate dehydrogenase. Where the engineered formate dehydrogenase is capable of catalyzing a conversion. L'invention concerne des polypeptides et des acides nucléiques codant pour des formiate déshydrogénases modifiées. L'invention concerne également des cellules exprimant une formiate déshydrogénase modifiée. La divulgation concerne en outre des procédés de production d'un composé biodérivé comprenant la culture de cellules exprimant une formiate déshydrogénase modifiée.