GDF15 FUSION PROTEINS AND USES THEREOF

Provided are GDF15 fusion proteins and uses thereof. The fusion protein comprises an Fc variant and a GDF15 active domain, wherein the Fc variant has amino acid substitutions at position 356 and/or position 439 of the IgG Fc according to EU numbering and still has the ability to form homodimer. By f...

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Bibliographische Detailangaben

Hauptverfasser:	CHEN, Xiaofeng, HUANG, Limei, GONG, Qingwei, CAO, Rongbo, LI, Jing, YAN, Xingguo, XIAO, Lin, ZENG, Junnan, LI, Wenjia, WEI, Xiling, YAN, Jiangyu, HUANG, Danxia, LI, Zhaofeng
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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