ADENO-ASSOCIATED VIRAL VECTOR COMPOSITIONS AND METHODS OF PROMOTING MUSCLE REGENERATION
Provided are compositions comprising, and methods of administering, gene therapy vectors, particularly recombinant AAV vectors encoding AUF1 proteins for expression in muscle cells for restoring or increasing muscle mass, muscle function or performance, and/or reducing or reversing muscle atrophy. T...
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| creator | ABBADI, Dounia SCHNEIDER, Robert |
| description | Provided are compositions comprising, and methods of administering, gene therapy vectors, particularly recombinant AAV vectors encoding AUF1 proteins for expression in muscle cells for restoring or increasing muscle mass, muscle function or performance, and/or reducing or reversing muscle atrophy. The compositions and methods may be used for the treatment of subject suffering from sarcopenia, muscle degenerative disease or traumatic injury.
L'invention concerne des compositions comprenant des vecteurs de thérapie génique, ainsi que des méthodes d'administration de ces derniers, en particulier des vecteurs VAA recombinants codant pour des protéines AUF1 en vue de leur expression dans des cellules musculaires pour restaurer ou augmenter la masse musculaire, la fonction musculaire ou la performance musculaire, et/ou réduire ou inverser l'atrophie musculaire. Les compositions et les méthodes peuvent être utilisées pour le traitement d'un sujet souffrant de sarcopénie, d'une maladie dégénérative musculaire ou d'une lésion traumatique. |
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L'invention concerne des compositions comprenant des vecteurs de thérapie génique, ainsi que des méthodes d'administration de ces derniers, en particulier des vecteurs VAA recombinants codant pour des protéines AUF1 en vue de leur expression dans des cellules musculaires pour restaurer ou augmenter la masse musculaire, la fonction musculaire ou la performance musculaire, et/ou réduire ou inverser l'atrophie musculaire. Les compositions et les méthodes peuvent être utilisées pour le traitement d'un sujet souffrant de sarcopénie, d'une maladie dégénérative musculaire ou d'une lésion traumatique.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230309&DB=EPODOC&CC=WO&NR=2023004332A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230309&DB=EPODOC&CC=WO&NR=2023004332A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ABBADI, Dounia</creatorcontrib><creatorcontrib>SCHNEIDER, Robert</creatorcontrib><title>ADENO-ASSOCIATED VIRAL VECTOR COMPOSITIONS AND METHODS OF PROMOTING MUSCLE REGENERATION</title><description>Provided are compositions comprising, and methods of administering, gene therapy vectors, particularly recombinant AAV vectors encoding AUF1 proteins for expression in muscle cells for restoring or increasing muscle mass, muscle function or performance, and/or reducing or reversing muscle atrophy. The compositions and methods may be used for the treatment of subject suffering from sarcopenia, muscle degenerative disease or traumatic injury.
L'invention concerne des compositions comprenant des vecteurs de thérapie génique, ainsi que des méthodes d'administration de ces derniers, en particulier des vecteurs VAA recombinants codant pour des protéines AUF1 en vue de leur expression dans des cellules musculaires pour restaurer ou augmenter la masse musculaire, la fonction musculaire ou la performance musculaire, et/ou réduire ou inverser l'atrophie musculaire. Les compositions et les méthodes peuvent être utilisées pour le traitement d'un sujet souffrant de sarcopénie, d'une maladie dégénérative musculaire ou d'une lésion traumatique.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNyrEKwjAQANAsDqL-w4FzITT-wJFc20CTK8nZjqVInEQL9f8RwQ9wesvbqwkdRa4wZ7YehRyMPmEPI1nhBJbDwNmL55gBo4NA0rHLwA0MiQOLjy2Ea7Y9QaKWIiX87qPa3ZfHVk4_D-rckNiuKutrLtu63MqzvOeJa10brS_G1GjMf-sDrs0yKw</recordid><startdate>20230309</startdate><enddate>20230309</enddate><creator>ABBADI, Dounia</creator><creator>SCHNEIDER, Robert</creator><scope>EVB</scope></search><sort><creationdate>20230309</creationdate><title>ADENO-ASSOCIATED VIRAL VECTOR COMPOSITIONS AND METHODS OF PROMOTING MUSCLE REGENERATION</title><author>ABBADI, Dounia ; SCHNEIDER, Robert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2023004332A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>ABBADI, Dounia</creatorcontrib><creatorcontrib>SCHNEIDER, Robert</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ABBADI, Dounia</au><au>SCHNEIDER, Robert</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>ADENO-ASSOCIATED VIRAL VECTOR COMPOSITIONS AND METHODS OF PROMOTING MUSCLE REGENERATION</title><date>2023-03-09</date><risdate>2023</risdate><abstract>Provided are compositions comprising, and methods of administering, gene therapy vectors, particularly recombinant AAV vectors encoding AUF1 proteins for expression in muscle cells for restoring or increasing muscle mass, muscle function or performance, and/or reducing or reversing muscle atrophy. The compositions and methods may be used for the treatment of subject suffering from sarcopenia, muscle degenerative disease or traumatic injury.
L'invention concerne des compositions comprenant des vecteurs de thérapie génique, ainsi que des méthodes d'administration de ces derniers, en particulier des vecteurs VAA recombinants codant pour des protéines AUF1 en vue de leur expression dans des cellules musculaires pour restaurer ou augmenter la masse musculaire, la fonction musculaire ou la performance musculaire, et/ou réduire ou inverser l'atrophie musculaire. Les compositions et les méthodes peuvent être utilisées pour le traitement d'un sujet souffrant de sarcopénie, d'une maladie dégénérative musculaire ou d'une lésion traumatique.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | ADENO-ASSOCIATED VIRAL VECTOR COMPOSITIONS AND METHODS OF PROMOTING MUSCLE REGENERATION |
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