METHODS FOR PHYSICAL EXPANSION OF SAMPLES AND USES THEREOF

The invention provides a method for physical magnification of a sample while preserving biomolecules within the sample in the expanded state, and a method for producing expandable sample-hydrogel composites. Also provided is a hydrogel formulation for use in preparing the sample-hydrogel composite a...

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Hauptverfasser: XIAO, Keyu, SUN, Xiaoting, SUN, Cuiji, PIATKEVICH, Kiryl
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creator XIAO, Keyu
SUN, Xiaoting
SUN, Cuiji
PIATKEVICH, Kiryl
description The invention provides a method for physical magnification of a sample while preserving biomolecules within the sample in the expanded state, and a method for producing expandable sample-hydrogel composites. Also provided is a hydrogel formulation for use in preparing the sample-hydrogel composite and a related kit. The methods herein are compatible with different samples and sample staining methods and suitable for many utilities. L'invention concerne un procédé de grossissement physique d'un échantillon tout en préservant des biomolécules à l'intérieur de l'échantillon à l'état expansé, et un procédé de production de composites échantillon-hydrogel expansibles. L'invention concerne également une formulation d'hydrogel à utiliser dans la préparation du composite échantillon-hydrogel et un kit associé. Les procédés de l'invention sont compatibles avec différents échantillons et procédés de coloration d'échantillons, et appropriés pour de nombreuses utilisations.
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subjects INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
PHYSICS
TESTING
title METHODS FOR PHYSICAL EXPANSION OF SAMPLES AND USES THEREOF
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