SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID
The invention discloses a method for preparation of spray dried solid dispersions (SDD)comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, this su...
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creator | ADAM, Molly VODAK, David BAUMANN, John BENNETTE, Nathan GRASS, Michael MILLER, Warren PLUNTZE, Amanda MORGEN, Michael REGAN, Daniel |
description | The invention discloses a method for preparation of spray dried solid dispersions (SDD)comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, this supersaturated solution further comprising DISPPOL.
L'invention divulgue un procédé de préparation de dispersions solides séchées par atomisation (SDD) comprenant un principe pharmaceutique actif (API) et un polymère de dispersion (DISPPOL), le séchage par atomisation étant effectué avec une solution sursaturée d'API dans un mélange de solvants comprenant deux solvants, cette solution sursaturée comprenant en outre du DISPPOL. |
format | Patent |
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L'invention divulgue un procédé de préparation de dispersions solides séchées par atomisation (SDD) comprenant un principe pharmaceutique actif (API) et un polymère de dispersion (DISPPOL), le séchage par atomisation étant effectué avec une solution sursaturée d'API dans un mélange de solvants comprenant deux solvants, cette solution sursaturée comprenant en outre du DISPPOL.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221215&DB=EPODOC&CC=WO&NR=2022258759A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221215&DB=EPODOC&CC=WO&NR=2022258759A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ADAM, Molly</creatorcontrib><creatorcontrib>VODAK, David</creatorcontrib><creatorcontrib>BAUMANN, John</creatorcontrib><creatorcontrib>BENNETTE, Nathan</creatorcontrib><creatorcontrib>GRASS, Michael</creatorcontrib><creatorcontrib>MILLER, Warren</creatorcontrib><creatorcontrib>PLUNTZE, Amanda</creatorcontrib><creatorcontrib>MORGEN, Michael</creatorcontrib><creatorcontrib>REGAN, Daniel</creatorcontrib><title>SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID</title><description>The invention discloses a method for preparation of spray dried solid dispersions (SDD)comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, this supersaturated solution further comprising DISPPOL.
L'invention divulgue un procédé de préparation de dispersions solides séchées par atomisation (SDD) comprenant un principe pharmaceutique actif (API) et un polymère de dispersion (DISPPOL), le séchage par atomisation étant effectué avec une solution sursaturée d'API dans un mélange de solvants comprenant deux solvants, cette solution sursaturée comprenant en outre du DISPPOL.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAIDghyjFRwCYr09HNX8HdTcAzwVPD0UwgODXANCnYMCQ1yDHF1UQj29wkN8fT3C1YI9wzxUHDzD_L1dFZwdPZ04WFgTUvMKU7lhdLcDMpuriHOHrqpBfnxqcUFicmpeakl8eH-RgZGRkamFuamlo6GxsSpAgBpUivG</recordid><startdate>20221215</startdate><enddate>20221215</enddate><creator>ADAM, Molly</creator><creator>VODAK, David</creator><creator>BAUMANN, John</creator><creator>BENNETTE, Nathan</creator><creator>GRASS, Michael</creator><creator>MILLER, Warren</creator><creator>PLUNTZE, Amanda</creator><creator>MORGEN, Michael</creator><creator>REGAN, Daniel</creator><scope>EVB</scope></search><sort><creationdate>20221215</creationdate><title>SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID</title><author>ADAM, Molly ; VODAK, David ; BAUMANN, John ; BENNETTE, Nathan ; GRASS, Michael ; MILLER, Warren ; PLUNTZE, Amanda ; MORGEN, Michael ; REGAN, Daniel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022258759A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>ADAM, Molly</creatorcontrib><creatorcontrib>VODAK, David</creatorcontrib><creatorcontrib>BAUMANN, John</creatorcontrib><creatorcontrib>BENNETTE, Nathan</creatorcontrib><creatorcontrib>GRASS, Michael</creatorcontrib><creatorcontrib>MILLER, Warren</creatorcontrib><creatorcontrib>PLUNTZE, Amanda</creatorcontrib><creatorcontrib>MORGEN, Michael</creatorcontrib><creatorcontrib>REGAN, Daniel</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ADAM, Molly</au><au>VODAK, David</au><au>BAUMANN, John</au><au>BENNETTE, Nathan</au><au>GRASS, Michael</au><au>MILLER, Warren</au><au>PLUNTZE, Amanda</au><au>MORGEN, Michael</au><au>REGAN, Daniel</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID</title><date>2022-12-15</date><risdate>2022</risdate><abstract>The invention discloses a method for preparation of spray dried solid dispersions (SDD)comprising an active pharmaceutical ingredient (API) and a dispersion polymer (DISPPOL), wherein the spray drying is done with a supersaturated solution of API in a solvent mixture comprising two solvents, this supersaturated solution further comprising DISPPOL.
L'invention divulgue un procédé de préparation de dispersions solides séchées par atomisation (SDD) comprenant un principe pharmaceutique actif (API) et un polymère de dispersion (DISPPOL), le séchage par atomisation étant effectué avec une solution sursaturée d'API dans un mélange de solvants comprenant deux solvants, cette solution sursaturée comprenant en outre du DISPPOL.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | SPRAY DRYING OF API IN SUPERSATURATED SOLUTIONS WITH FORMIC ACID |
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