MYELOID CELLS OVEREXPRESSING BCL2
The present invention relates to isolated modified myeloid cell, a progenitor thereof, or a progeny thereof, encoding an antigen recognizing receptor, wherein said myeloid cell or progenitor thereof has been further modified to overexpress BCL2. The present invention further relates to therapeutic a...
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| creator | LAHAYE, Xavier AMIGORENA, Sebastian MANEL, Nicolas SAITAKIS, Michael FUENTEALBA, Jaime |
| description | The present invention relates to isolated modified myeloid cell, a progenitor thereof, or a progeny thereof, encoding an antigen recognizing receptor, wherein said myeloid cell or progenitor thereof has been further modified to overexpress BCL2. The present invention further relates to therapeutic application in particular in the field of adoptive therapy of said modified myeloid cells.
La présente invention concerne une cellule myéloïde modifiée isolée, un progéniteur de celle-ci, ou une descendance de celle-ci, codant pour un récepteur reconnaissant l'antigène, ladite cellule myéloïde ou son progéniteur ayant été encore modifié pour surexprimer BCL2. La présente invention concerne en outre l'application thérapeutique en particulier dans le domaine de la thérapie adoptive desdites cellules myéloïdes modifiées. |
| format | Patent |
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La présente invention concerne une cellule myéloïde modifiée isolée, un progéniteur de celle-ci, ou une descendance de celle-ci, codant pour un récepteur reconnaissant l'antigène, ladite cellule myéloïde ou son progéniteur ayant été encore modifié pour surexprimer BCL2. La présente invention concerne en outre l'application thérapeutique en particulier dans le domaine de la thérapie adoptive desdites cellules myéloïdes modifiées.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221201&DB=EPODOC&CC=WO&NR=2022248602A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221201&DB=EPODOC&CC=WO&NR=2022248602A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LAHAYE, Xavier</creatorcontrib><creatorcontrib>AMIGORENA, Sebastian</creatorcontrib><creatorcontrib>MANEL, Nicolas</creatorcontrib><creatorcontrib>SAITAKIS, Michael</creatorcontrib><creatorcontrib>FUENTEALBA, Jaime</creatorcontrib><title>MYELOID CELLS OVEREXPRESSING BCL2</title><description>The present invention relates to isolated modified myeloid cell, a progenitor thereof, or a progeny thereof, encoding an antigen recognizing receptor, wherein said myeloid cell or progenitor thereof has been further modified to overexpress BCL2. The present invention further relates to therapeutic application in particular in the field of adoptive therapy of said modified myeloid cells.
La présente invention concerne une cellule myéloïde modifiée isolée, un progéniteur de celle-ci, ou une descendance de celle-ci, codant pour un récepteur reconnaissant l'antigène, ladite cellule myéloïde ou son progéniteur ayant été encore modifié pour surexprimer BCL2. La présente invention concerne en outre l'application thérapeutique en particulier dans le domaine de la thérapie adoptive desdites cellules myéloïdes modifiées.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFD0jXT18fd0UXB29fEJVvAPcw1yjQgIcg0O9vRzV3By9jHiYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBkZGRiYWZgZGjobGxKkCAKZ3Ix0</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>LAHAYE, Xavier</creator><creator>AMIGORENA, Sebastian</creator><creator>MANEL, Nicolas</creator><creator>SAITAKIS, Michael</creator><creator>FUENTEALBA, Jaime</creator><scope>EVB</scope></search><sort><creationdate>20221201</creationdate><title>MYELOID CELLS OVEREXPRESSING BCL2</title><author>LAHAYE, Xavier ; AMIGORENA, Sebastian ; MANEL, Nicolas ; SAITAKIS, Michael ; FUENTEALBA, Jaime</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022248602A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LAHAYE, Xavier</creatorcontrib><creatorcontrib>AMIGORENA, Sebastian</creatorcontrib><creatorcontrib>MANEL, Nicolas</creatorcontrib><creatorcontrib>SAITAKIS, Michael</creatorcontrib><creatorcontrib>FUENTEALBA, Jaime</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LAHAYE, Xavier</au><au>AMIGORENA, Sebastian</au><au>MANEL, Nicolas</au><au>SAITAKIS, Michael</au><au>FUENTEALBA, Jaime</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MYELOID CELLS OVEREXPRESSING BCL2</title><date>2022-12-01</date><risdate>2022</risdate><abstract>The present invention relates to isolated modified myeloid cell, a progenitor thereof, or a progeny thereof, encoding an antigen recognizing receptor, wherein said myeloid cell or progenitor thereof has been further modified to overexpress BCL2. The present invention further relates to therapeutic application in particular in the field of adoptive therapy of said modified myeloid cells.
La présente invention concerne une cellule myéloïde modifiée isolée, un progéniteur de celle-ci, ou une descendance de celle-ci, codant pour un récepteur reconnaissant l'antigène, ladite cellule myéloïde ou son progéniteur ayant été encore modifié pour surexprimer BCL2. La présente invention concerne en outre l'application thérapeutique en particulier dans le domaine de la thérapie adoptive desdites cellules myéloïdes modifiées.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | MYELOID CELLS OVEREXPRESSING BCL2 |
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