IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS
Described herein, inter alia, are imidazopyridine derivatives (I), pharmaceutically acceptable salts and tautomers thereof, compounds, combinations and medicaments containing said compounds and processes for their preparation. In embodiments, the imidazopyridine derivatives can be used as regulators...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | ZANG, Jingcun HSIEH, Ming TAO, Chunlin |
| description | Described herein, inter alia, are imidazopyridine derivatives (I), pharmaceutically acceptable salts and tautomers thereof, compounds, combinations and medicaments containing said compounds and processes for their preparation. In embodiments, the imidazopyridine derivatives can be used as regulators of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, infectious diseases and as vaccine adjuvants.
L'invention concerne, entre autres, des dérivés d'imidazopyridine (I), des sels pharmaceutiquement acceptables et des tautomères de ceux-ci, des composés, des associations et des médicaments contenant lesdits composés et des procédés pour leur préparation. Dans des modes de réalisation, les dérivés d'imidazopyridine peuvent être utilisés en tant que régulateurs d'un stimulateur de gènes d'interféron (STING) et d'une voie de signalisation associée de celui-ci, et peuvent traiter et/ou soulager de manière efficace de multiples types de maladies, y compris mais de façon non limitative des tumeurs malignes, des inflammations, des maladies auto-immunes, des maladies infectieuses et en tant qu'adjuvants de vaccins. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO2022246597A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO2022246597A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO2022246597A13</originalsourceid><addsrcrecordid>eNrjZND19PV0cYzyD4gM8nTx9HNVcHEN8gxzDPEMcw1WcAxWCA7x9HNXcHT39_MMDgnmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBkZGRiZmppbmjobGxKkCAH8pJso</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS</title><source>esp@cenet</source><creator>ZANG, Jingcun ; HSIEH, Ming ; TAO, Chunlin</creator><creatorcontrib>ZANG, Jingcun ; HSIEH, Ming ; TAO, Chunlin</creatorcontrib><description>Described herein, inter alia, are imidazopyridine derivatives (I), pharmaceutically acceptable salts and tautomers thereof, compounds, combinations and medicaments containing said compounds and processes for their preparation. In embodiments, the imidazopyridine derivatives can be used as regulators of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, infectious diseases and as vaccine adjuvants.
L'invention concerne, entre autres, des dérivés d'imidazopyridine (I), des sels pharmaceutiquement acceptables et des tautomères de ceux-ci, des composés, des associations et des médicaments contenant lesdits composés et des procédés pour leur préparation. Dans des modes de réalisation, les dérivés d'imidazopyridine peuvent être utilisés en tant que régulateurs d'un stimulateur de gènes d'interféron (STING) et d'une voie de signalisation associée de celui-ci, et peuvent traiter et/ou soulager de manière efficace de multiples types de maladies, y compris mais de façon non limitative des tumeurs malignes, des inflammations, des maladies auto-immunes, des maladies infectieuses et en tant qu'adjuvants de vaccins.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221201&DB=EPODOC&CC=WO&NR=2022246597A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20221201&DB=EPODOC&CC=WO&NR=2022246597A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZANG, Jingcun</creatorcontrib><creatorcontrib>HSIEH, Ming</creatorcontrib><creatorcontrib>TAO, Chunlin</creatorcontrib><title>IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS</title><description>Described herein, inter alia, are imidazopyridine derivatives (I), pharmaceutically acceptable salts and tautomers thereof, compounds, combinations and medicaments containing said compounds and processes for their preparation. In embodiments, the imidazopyridine derivatives can be used as regulators of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, infectious diseases and as vaccine adjuvants.
L'invention concerne, entre autres, des dérivés d'imidazopyridine (I), des sels pharmaceutiquement acceptables et des tautomères de ceux-ci, des composés, des associations et des médicaments contenant lesdits composés et des procédés pour leur préparation. Dans des modes de réalisation, les dérivés d'imidazopyridine peuvent être utilisés en tant que régulateurs d'un stimulateur de gènes d'interféron (STING) et d'une voie de signalisation associée de celui-ci, et peuvent traiter et/ou soulager de manière efficace de multiples types de maladies, y compris mais de façon non limitative des tumeurs malignes, des inflammations, des maladies auto-immunes, des maladies infectieuses et en tant qu'adjuvants de vaccins.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2022</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND19PV0cYzyD4gM8nTx9HNVcHEN8gxzDPEMcw1WcAxWCA7x9HNXcHT39_MMDgnmYWBNS8wpTuWF0twMym6uIc4euqkF-fGpxQWJyal5qSXx4f5GBkZGRiZmppbmjobGxKkCAH8pJso</recordid><startdate>20221201</startdate><enddate>20221201</enddate><creator>ZANG, Jingcun</creator><creator>HSIEH, Ming</creator><creator>TAO, Chunlin</creator><scope>EVB</scope></search><sort><creationdate>20221201</creationdate><title>IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS</title><author>ZANG, Jingcun ; HSIEH, Ming ; TAO, Chunlin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2022246597A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2022</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>ZANG, Jingcun</creatorcontrib><creatorcontrib>HSIEH, Ming</creatorcontrib><creatorcontrib>TAO, Chunlin</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ZANG, Jingcun</au><au>HSIEH, Ming</au><au>TAO, Chunlin</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS</title><date>2022-12-01</date><risdate>2022</risdate><abstract>Described herein, inter alia, are imidazopyridine derivatives (I), pharmaceutically acceptable salts and tautomers thereof, compounds, combinations and medicaments containing said compounds and processes for their preparation. In embodiments, the imidazopyridine derivatives can be used as regulators of a stimulator of interferon genes (STING) and a related signal path thereof, and can effectively treat and/or relieve multiple types of diseases, including but not limited to malignant tumors, inflammations, autoimmune diseases, infectious diseases and as vaccine adjuvants.
L'invention concerne, entre autres, des dérivés d'imidazopyridine (I), des sels pharmaceutiquement acceptables et des tautomères de ceux-ci, des composés, des associations et des médicaments contenant lesdits composés et des procédés pour leur préparation. Dans des modes de réalisation, les dérivés d'imidazopyridine peuvent être utilisés en tant que régulateurs d'un stimulateur de gènes d'interféron (STING) et d'une voie de signalisation associée de celui-ci, et peuvent traiter et/ou soulager de manière efficace de multiples types de maladies, y compris mais de façon non limitative des tumeurs malignes, des inflammations, des maladies auto-immunes, des maladies infectieuses et en tant qu'adjuvants de vaccins.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_WO2022246597A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T05%3A10%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=ZANG,%20Jingcun&rft.date=2022-12-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO2022246597A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |